Sleep movements and respiratory coupling as a biobehavioral metric for early Alzheimer’s disease in independently dwelling adults

Table 4 Nocturnal Actigraphy in MCI-DX, MCI-CON and NC Groups

Actigraphy Variable	MCI-DX	MCI-CON	NC	p
Wake Bout Time (WBT, min)	2.67	2.79^a	2.32^a	0.036^a
Sleep Fragmentation (SF, freq)	45.75^a,b	35.62^b	32.79^a	0.008^a; 0.041^b
Total Sleep Time (TST, min)	379.94^a	431.89	454.30^a	0.01^a
Sleep Efficiency (SE, %)	76.74^a	83.65^a	82.01	0.021^a
Sleep Latency (SL, min)	44.08^a	13.84^a	27.85	0.008^a
Mean Activity Score (MA, freq)	13.63	18.67^a	12.76^a	0.006^a

Note. Multivariable Regression of MCI status and Actigraphy (mean = 6.7 nights) measures adjusted with covariates age, current depressive symptoms, years of education, and BMI were significant for these parameters WBT, SF, TST, SE, SL, M.A. (p < .000); post-hoc group differences are shown (p < .001-.05) with superscript letters (a,b) reflect pairwise differences. No group findings emerged for time in bed, actual sleep percent, actual wake percent, sleep bouts, wake bouts, sleep bout time, immobile percent time, number of minutes moving, moving percent time, number of immobile phases, mean length immobility, mean one minute immobility, total activity score, wake after sleep onset (WASO), S.D. of activity counts, or largest activity count

ISSN: 1471-2318