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Table 2 MCI Severity and Neurocognitive Memory Domain Test Scores

From: Sleep movements and respiratory coupling as a biobehavioral metric for early Alzheimer’s disease in independently dwelling adults

Neurocognitive Test

MCI Status

  

Ranking

MCI-DX

(n= 17)

MCI-CON

(n= 33)

NC

(n= 45)

Post-hoc (p)

HVLT-R Total Recall

13.57 (1.2)

17.95 (0.7)

23.68 (0.7)

MCI-DX < MCI-CON < NC (< 0.001–0.002)

HVLT-R Delayed Recall

2.59 (0.6)

5.11 (0.4)

8.54 (0.3)

MCI-DX < MCI-CON < NC (< 0.001–0.001)

HVLT-R Retention %

47.17 (7.7)

69.13 (4.6)

88.57 (4.4)

MCI-DX < MCI-CON < NC (< 0.003–0.016)

BVMT-R Trial 1

1.27 (0.5)

2.39 (0.3)

3.23 (0.3)

MCI-CON < NC (0.046); MCI-DX < NC (0.001)

BVMT-R Trial 2

1.90 (0.6)

4.25 (0.4)

5.45 (0.4)

MCI-DX < MCI-CON < NC (< 0.001–0.022)

BVMT-R Trial 3

1.83 (0.7)

5.69 (0.4)

7.14 (0.4)

MCI-DX < MCI-CON < NC (< 0.001–0.016)

BVMT-R Total Recall

4.61 (1.5)

12.32 (0.9)

15.78 (0.9)

MCI-DX < MCI-CON < NC (< 0.001–0.008)

BVMT-R Learning

1.70 (0.7)

3.4 (0.4)

4.07 (0.4)

MCI-DX < NC (0.002); MCI-DX < MCI-CON (0.028)

BVMT-R Delayed Recall

1.86 (0.8)

4.87 (0.4)

6.68 (0.4)

MCI-DX < MCI-CON < NC (< 0.001–0.005)

BVMT-R Retention %

64.19 (10.1)

84.5 (6.0)

88.81 (5.9)

MCI-DX < NC (0.037)

BNT Total Score

13.22 (0.4)

14.16 (0.2)

14.25 (0.2)

MCI-DX < MCI-CON (0.028)

  1. Note. HVLT-R Hopkins Verbal Learning Test-Revised, BVMT-R Brief Visuospatial Memory Test-Revised, BNT Boston Naming Test. All neurocognitive variables are expressed as raw scores expressed as group means and standard error. Multivariable regression applied with group factor and neurocognitive tests dependent variables adjusted for age and depression was significant for all tests; post-hoc group comparisons are shown in parentheses. MCI-DX = Physician diagnosed MCI; MCI-CON = Expert panel consensus decision based on clinical status and neuro-cognitive assessments; NC = Normal cognition