Table 1 Demographics and Health History in MCI-DX, MCI-CON, and NC Groups
Variable (µ ± SE or % (n)) | MCI-DX (n = 17) | MCI-CON (n = 33) | NC (n = 45) | p-value |
|---|---|---|---|---|
Age, y | 75.94 ± 1.39 | 73.42 ± 1.24 | 71.31 ± 0.91 | 0.038 |
Female | 70.6% (12) | 60.6% (20) | 77.8% (35) | n.s |
Race (% white) | 100% (17) | 100% (33) | 97.8% (44) | n.s |
Years of education | 15.07 ± 0.84 | 15.55 ± 0.53 | 15.60 ± 0.35 | n.s |
MoCA | 19.76 ± 0.78 | 22.45 ± 0.48 | 26.73 ± 0.30 | 0.001 |
Lifestyle factors | ||||
Drinking alcohol | 33.3% (5) | 66.7% (22) | 62.2% (28) | n.s |
Current use of sleep medicationa | 60% (9) | 33.3% (11) | 42.2% (19) | n.s |
Current or former smoker | 53.3% (8) | 54.5% (18) | 46.7% (21) | n.s |
Body mass index (BMI) | 24.65 ± 1.38 | 29.37 ± 1.09 | 27.60 ± 0.86 | 0.049 |
OSA | 11.8% (2) | 36.4% (12) | 17.8% (8) | n.s |
Diabetes | 6.7% (1) | 27.3% (9) | 11.1% (5) | n.s |
Heart attack or cardiac arrest | 20% (3) | 12.1% (4) | 11.1% (5) | n.s |
Cardiovascular disease | 6.7% (1) | 24.2% (8) | 13.3% (6) | n.s |
Cerebrovascular disease | 33.3% (5) | 9.1% (3) | 6.7% (3) | n.s |
Traumatic brain injury (TBI) | 26.7% (4) | 15.2% (5) | 15.6% (7) | n.s |
Hypercholesterolemia | 53.3% (8) | 36.4% (12) | 42.2% (19) | n.s |
Hypertension | 33.3% (5) | 54.5% (18) | 34.1% (15) | n.s |
Arthritis | 46.7% (7) | 69.7% (23) | 48.9% (22) | n.s |
Thyroid disease | 40% (6) | 18.2% (6) | 33.3% (15) | n.s |
Current depressive symptomsb | 46.7% (7) | 33.3% (11) | 13.3% (6) | 0.036 |