Fig. 7
From: Functional activity level reported by an informant is an early predictor of Alzheimer’s disease
Model exploration: PDP of the FAQ and SHAP auto-cohort split. A Illustrates the marginal effect the FAQ total score have on the RF model. The X-axis represents the range of FAQ values (0-30), and the Y-axis shows changes in the prediction. Positive values represent the contribution of the FAQ to the increase in the odds to convert to AD. The shaded area represents the standard deviation. The individual composition expectation (ICE) plot is superimposed on the PDP. B Two cohorts are optimally separated by the SHAP values by applying auto-cohort feature of explanation, utilizing a DecisionTreeRegressor from scikit-learn. By this, separation is given between those scoring less than 1.5 and those \(\ge\) 1.5 in the FAQ. Hence, creating two cohorts with 65 and 75 subjects in each. The bar plot displays the mean SHAP values for each group for each feature