Table 3 Performance of NEWS2 ≥ 5 to predict poor outcome by frailty status
Sensitivity (95% CI) | Specificity (95% CI) | PPV (95% CI) | NPV (95% CI) | AUROC (95% CI) | |
|---|---|---|---|---|---|
Prediction of in-hospital mortality | |||||
Without frailty, (CFS < 4) | 85.7% (63.7%-97.0%) | 59.8% (54.2%-65.2%) | 12.2% (7.4%-18.7%) | 98.5% (95.6%-99.7%) | 0.73 (0.65-0.81) |
With frailty, (CFS ≥ 4) | 61.1% (35.7%-82.7%) | 61.5% (47.0%-74.7%) | 35.5% (19.2%-54.6%) | 82.1% (66.5%-92.5%) | 0.61 (0.48-0.75) |
Prediction of critical disease | |||||
Without frailty, (CFS < 4) | 78.4% (68.4%-86.5%) | 69.3% (63.2%-74.9%) | 46.9% (38.7%-55.3%) | 90.3% (85.2%-94.0%) | 0.74 (0.69-0.79) |
With frailty, (CFS ≥ 4) | 61.9% (38.4%-81.9%) | 63.3% (48.3%-76.6%) | 41.9% (24.5%-60.9%) | 79.5% (63.5%-90.7%) | 0.63 (0.50-0.75) |