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Table 2 Parameter estimates (absolute) of the linear mixed model (LMM; Model 3, REML estimation) for the primary and secondary outcome variables using both the intention-to-treat (ITT) and per-protocol (PP) versions of the data set

From: Local, collaborative, stepped, and personalized care management for older people with chronic diseases – results from the randomized controlled LoChro-trial

 

Composite Score

WHODAS

PHQ-9

PACIC

HRQL

LS

 

ITT

PP

ITT

PP

ITT

PP

ITT

PP

ITT

PP

ITT

PP

Fixed Parameters

 Intercept

9.78

-1.59

1.93

-9.35

15.69

4.84

63.97

71.34**

5.16***

7.05***

3.91*

6.14**

 Group

      

 Time [T0-T2]

7.88***

9.28***

11.04***

13.28***

4.82*

5.28*

    

 Time [T1-T2]

4.53*

4.85**

7.05***

7.72***

    

 Time*Group [T0-T2]

      

 Time*Group [T1-T2]

      

 Gender

6.14***

6.28***

6.54***

6.45***

5.58***

5.85***

-5.16** 5.20**

-.58***

-.63***

-.54*

-.58**

 Age

      

 Mulitmorbidity

1.26***

1.34***

1.59***

1.64***

.91***

1.00***

 

-.61*

-.07**

-.07**

 

 Depression

6.99**

6.72**

  

9.98***

8.92***

-6.91**

 

1.15***

1.08***

 Diabetes

       

 Family_1 (= single)

    

.62*

 

1.09**

.95*

 Family_2 (= divorced)

      

 Family_3 (= widowed)

      

 Home_1 (= care home)

       

 Home_2 (= senior appartment)

       

 Insurance_1 (= assistance)

      

 Insurance_2 (= private)

5.59*

5.89*

7.03**

7.02*

    

-.68*

-.67*

 School_1 (= CSE)

      

 School_2 (= GCSE)

4.09*

4.58*

6.03**

6.71**

    

 School_3 (= none)

       

 Recruitment_1 (= Ambulance)

       

 Recruitment_2 (= Flyer)

   

-7.75***

6.73***

  

 Setting

       

Random Effects

 Individual Intercept

136.68***

134.41***

206.70***

201.31***

116.03***

110.28***

130.95***

129.72***

1.56***

1.44***

2.05***

2.07***

 Repeated Measure

136.52***

133.28***

173.08***

167.44***

157.14***

154.53***

371.58***

361.56***

1.46***

1.59***

3.49***

1.48***

1.63***

3.38***

1.87***

2.39***

3.70***

1.80***

2.49***

3.83***

  1. Note: M3 = full model (including all relevant specifications, Variance Components [VC] & Scaled Identity [ID] Matrix), the difference in display of the random repeated measure effect stems from different residual matrices chosen for the best fitting model (VC and Degrees of Freedom [DF], respectively), ITT = Intention-To-Treat, PP = Per-Protocol, REML = Residual Maximum Likelihood Estimation, CSE = Certificate of Secondary Education, GCSE = General Certificate of Secondary Education. ***p < .001; **p < .01; *p < .05. All non-significant parameters have been omitted for clarity reasons