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Table 2 AUC-values, cut-off limits and their sensitivities, specificities and positive and negative predictive values for the 50-parameter combined index and for the reduced indexes in predicting 10-year institutionalization and mortality

From: A novel easy-to-use index to predict institutionalization and death in older population – a 10-year population-based follow-up study

 

AUC (95% CI)

Cut-off limit (scale)

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

Institutionalization

50-parameter combined index

0.71

(0.66–0.75)

 ≥ 0.25*

(0–1)

38.3

84.9

29.4

89.3

Reduced index without age and gender

0.74

(0.70–0.78)

 ≥ 2**

(0–3)

71.0

71.8

30.2

93.5

Reduced index with age and gender

0.78

(0.75–0.82)

 ≥ 4**

(0–7)

74.7

69.4

29.6

94.1

Mortality

50-parameter combined index

0.77

(0.74–0.80)

 ≥ 0.25*

(0–1)

42.5

92.0

74.2

74.7

Reduced index without age and gender

0.79

(0.77–0.82)

 ≥ 5**

(0–9)

61.8

84.2

69.5

79.2

Reduced index with age and gender

0.83

(0.80–0.85)

 ≥ 8**

(0–13)

77.0

75.8

64.9

85.1

  1. Abbreviations: AUC Area under the curve, CI Confidence interval, PPV Positive predictive value, NPV Negative predictive value
  2. *Habitual cut-off limit for a frailty index
  3. **Best cut-off limit defined by Youden-index