The effect of all-cause hospitalization on cognitive decline in older adults: a longitudinal study using databases of the National Health Insurance Service and the memory clinics of a self-run hospital

Table 2 Mixed models for estimating cognitive changes according to the hospitalization-related variables

Variables of interest	Models	β	SE	P value
Hospitalization or not	Model I^a	1.0141	0.0458	< 0.001
	Model II^b	1.0144	0.0458	< 0.001
	Model III^c	1.0583	0.0492	< 0.001
Total number of hospitalizations	Model I^a	0.0246	0.0053	< 0.001
	Model II^b	0.0246	0.0053	< 0.001
	Model III^c	0.0208	0.0056	< 0.001
Hospitalization days	Model I^a	0.0024	0.0004	< 0.001
	Model II^b	0.0024	0.0004	< 0.001
	Model III^c	0.0022	0.0004	< 0.001

Abbreviations: APOE Apolipoprotein E, CDR-SB Clinical dementia rating-sum of boxes, SE Standard error
^aModel I: CDR-SB = variable of interest × time + variable of interest + time + sex + CDR-SB (baseline)
^bModel II: CDR-SB = Model I + APOEε4 + age + hypertension + diabetes
^cModel III: CDR-SB = Model II + education year + ischemic burden

ISSN: 1471-2318