Association between physical activity and risk of renal function decline and mortality in community-dwelling older adults: a nationwide population-based cohort study

Table 3 Associations between the levels of physical activity and clinical outcomes in the elderly

	Crude			Model 1			Model 2			Model 3
	HR	95% CI		HR	95% CI		HR	95% CI		HR	95% CI
	HR	Lower	Upper	HR	Lower	Upper	HR	Lower	Upper	HR	Lower	Upper
All-cause mortality
Inactive (Ref.)	1			1			1			1
Low-active	0.82	0.78	0.86	0.83	0.79	0.87	0.84	0.80	0.89	0.84	0.80	0.89
Active	0.77	0.71	0.83	0.73	0.68	0.79	0.76	0.70	0.82	0.76	0.70	0.82
p for trend	< 0.001			< 0.001			< 0.001			< 0.001
Cardiovascular mortality
Inactive (Ref.)	1			1			1			1
Low-active	0.72	0.63	0.81	0.75	0.66	0.85	0.75	0.66	0.85	0.75	0.67	0.85
Active	0.61	0.50	0.74	0.63	0.52	0.77	0.64	0.53	0.78	0.64	0.53	0.78
p for trend	< 0.001			< 0.001			< 0.001			< 0.001
≥ 50% eGFR decline
Inactive (Ref.)	1			1			1			1
Low-active	0.87	0.77	0.97	0.90	0.80	1.03	0.88	0.78	0.99	0.91	0.81	1.03
Active	0.75	0.63	0.89	0.82	0.68	0.97	0.78	0.65	0.93	0.81	0.68	0.97
p for trend	0.001			0.014			0.004			0.021

Analysis: A p for trend obtained from the Wald test, and hazard ratios with 95% confidence intervals were obtained from Cox proportional hazards regression analysis
Model 1: age, sex, body mass index, Model 2: Model 1 + smoking, alcohol, income, cerebrovascular disease, heart disease, diabetes mellitus, hypertension, dyslipidemia, Model 3: Model 2 + systolic blood pressure, fasting glucose, total cholesterol, baseline estimated glomerular filtration rate

ISSN: 1471-2318