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Table 3 Subgroup analysis of the association between eGDR and risk of CVD

From: Estimated glucose disposal rate and risk of cardiovascular disease: evidence from the China Health and Retirement Longitudinal Study

Characteristics

eGDR(mg/kg/min)

P value

P-interaction

 < 8.92

8.92–10.41

10.41–11.26

 ≥ 11.26

Sex

 Male

1.00(Ref)

0.91(0.74–1.13)

0.70(0.57–0.87)

0.59(0.47–0.74)

 < 0.001

0.005

 Female

1.00(Ref)

0.98(0.83–1.16)

0.67(0.55–0.82)

0.57(0.46–0.70)

 < 0.001

 

Diabetes

 No

1.00(Ref)

0.98(0.85–1.13)

0.70(0.60–0.81)

0.59(0.50–0.69)

 < 0.001

0.110

 Yes

1.00(Ref)

0.97(0.45–2.09)

0.89(0.50–1.58)

0.75(0.56–0.96)

0.003

 

Age, years

  < 60

1.00(Ref)

0.91(0.76–1.10)

0.64(0.52–0.78)

0.55(0.44–0.68)

 < 0.001

 < 0.001

  ≥ 60

1.00(Ref)

1.04(0.87–1.25)

0.78(0.63–0.95)

0.65(0.53–0.81)

 < 0.001

 

Place of residence

 Urban

1.00(Ref)

0.87(0.74–1.04)

0.66(0.55–0.78)

0.57(0.47–0.68)

 < 0.001

0.681

 Rural

1.00(Ref)

1.10(0.89–1.36)

0.73(0.56–0.93)

0.57(0.43–0.76)

 < 0.001

 

Smoking

 No

1.00(Ref)

0.97(0.82–1.14)

0.68(0.57–0.82)

0.59(0.48–0.72)

 < 0.001

0.465

 Yes

1.00(Ref)

0.93(0.75–1.16)

0.69(0.55–0.87)

0.57(0.45–0.72)

 < 0.001

 

Drinking

 No

1.00(Ref)

0.99(0.84–1.17)

0.70(0.58–0.84)

0.61(0.50–0.74)

 < 0.001

0.954

 Yes

1.00(Ref)

0.90(0.72–1.11)

0.68(0.54–0.85)

0.54(0.42–0.69)

 < 0.001

 

Education level, n (%)

 Below primary school

1.00(Ref)

0.98(0.78–1.23)

0.67(0.52–0.87)

0.60(0.46–0.78)

 < 0.001

0.114

 Primary school

1.00(Ref)

0.98(0.79–1.21)

0.73(0.58–0.91)

0.55(0.43–0.71)

 < 0.001

 

 Middle school

1.00(Ref)

1.07(0.78–1.47)

0.72(0.51–1.02)

0.69(0.47–0.98)

0.022

 

 High school or above

1.00(Ref)

0.73(0.49–1.09)

0.67(0.43–1.04)

0.52(0.32–0.84)

0.002

 

Anti-diabetes/hypertension drugs

 No

1.00(Ref)

0.91(0.79–1.05)

0.66(0.57–0.77)

0.56(0.47–0.65)

 < 0.001

0.002

 Yes

1.00(Ref)

1.02(0.66–1.29)

0.94(0.56–1.09)

0.58(0.43–0.77)

0.005

 
  1. In the multivariate models, confounding factors such age, sex, place of residence, education level, blood glucose, smoking, drinking, systolic blood pressure, physical activity, chronic diseases (dyslipidemia, chronic lung disease) and medications (anti-hypertensive and anti-dyslipidemic) were included unless the variable was used as a subgroup variable