Table 1 Demographic and clinical characteristics of subjects
Variable | Total(441) | Non-sarcopenia(280) | sarcopenia(161) | t/χ2/Z | p value |
|---|---|---|---|---|---|
Age(year) | 81.3 ± 9.5 | 79.6 ± 10.0 | 84.3 ± 7.7 | 5.458 | < 0.001 |
Gender(male) | 262 (59.4) | 155 (55.4) | 107 (66.5) | 5.225 | 0.022 |
Education | |||||
 Primary or below | 37 (8.4) | 14 (5.0) | 23 (14.3) | 3.274 | 0.001 |
 Middle school | 75 (17.0) | 43 (15.4) | 32 (19.9) | ||
 High school | 138 (31.3) | 90 (32.1) | 48 (29.8) | ||
 University or above | 191 (43.3) | 133 (47.5) | 58 (36.0) | ||
Smoking | 109 (24.7) | 58 (20.7) | 51 (31.7) | 6.602 | 0.010 |
Drinking | 129 (29.3) | 81 (28.9) | 48 (29.8) | 0.039 | 0.844 |
BMI(kg/m2) | |||||
 BMI < 18.5 | 11 (2.5) | 4 (1.4) | 7 (4.3) | 6.459 | < 0.001 |
 18.5 ≤ BMI < 24.0 | 176 (39.9) | 82 (29.3) | 94 (58.4) | ||
 24.0 ≤ BMI < 28.0 | 176 (39.9) | 131 (46.8) | 45 (28.0) | ||
 BMI ≥ 28.0 | 78 (17.7) | 63 (22.5) | 15 (9.3) | ||
Statin use | 338 (76.6) | 216 (77.1) | 122 (75.8) | 0.107 | 0.744 |
Diabetes | 197 (44.7) | 123 (43.9) | 74 (46.0) | 0.171 | 0.679 |
Hypertension | 286 (64.9) | 184 (65.7) | 102 (63.4) | 0.250 | 0.617 |
Kidney disease | 23 (5.2) | 15 (5.4) | 8 (5.0) | 0.031 | 0.860 |
MNA-SF | |||||
 Well-nourished | 343 (77.8) | 249 (88.9) | 94 (58.4) | 7.445 | < 0.001 |
 Malnutrition risk | 89 (20.2) | 29 (10.4) | 60 (37.3) | ||
 Malnutrition | 9 (2.0) | 2 (0.7) | 7 (4.3) | ||
Systolic BP (mmHg) | 134.7 ± 16.0 | 134.4 ± 15.4 | 135.1 ± 17.1 | 0.448 | 0.654 |
Diastolic BP (mmHg) | 72.7 ± 9.5 | 72.9 ± 9.1 | 72.3 ± 10.1 | 0.734 | 0.463 |
ALT(U/L) | 15.0 (12.0,22.0) | 16.0 (12.0,23.0) | 14.0 (11.0,21.0) | 2.184 | 0.029 |
AST(U/L) | 18.0 (15.0,22.0) | 18.0 (15.0,22.0) | 18.0 (15.0,21.0) | 0.560 | 0.575 |
BUN(mmol/L) | 5.6 (4.6,6.9) | 5.5 (4.6,6.8) | 5.8 (4.7,7.3) | 1.384 | 0.166 |
Scr(umol/L) | 76.0 (64.0,91.5) | 75.0 (63.9,87.4) | 78.0 (64.2,97.7) | 0.995 | 0.320 |
SUA(mg/dL) | 324.0 (265.0,390.5) | 325.0 (270.5390.5) | 322.0 (261.0,390.5) | 0.311 | 0.756 |
TG (mmol/L) | 1.1 (0.8,1.5) | 1.1 (0.8,1.6) | 1.0 (0.8,1.4) | 1.226 | 0.220 |
LDL-C (mmol/L) | 2.3 (1.7,2.8) | 2.3 (1.8,2.9) | 2.2 (1.7,2.8) | 0.563 | 0.573 |
HDL-C (mmol/L) | 1.1 (0.9,1.4) | 1.1 (0.9,1.3) | 1.1 (0.9,1.4) | 1.354 | 0.176 |
HbA1c(%) | 6.2 (5.8,6.8) | 6.2 (5.8,6.7) | 6.2 (5.8,6.9) | 0.298 | 0.766 |
K(mmol/L) | 3.9 (3.7,4.1) | 3.9 (3.7,4.1) | 3.9 (3.6,4.1) | 0.347 | 0.729 |
CRP(mg/L) | 1.3 (0.6,3.6) | 1.1 (0.5,2.9) | 1.7 (0.7,6.2) | 2.824 | 0.005 |
TSH(uIU/ml) | 2.0 (1.3,2.8) | 1.9 (1.3,2.7) | 2.2 (1.4,3.2) | 1.494 | 0.135 |
Hcy(umol/L) | 12.5 (10.3,15.5) | 11.7 (9.6,14.9) | 13.4 (11.6,17.3) | 4.919 | < 0.001 |
Hb(g/L) | 127.6 ± 17.4 | 129.1 ± 17.5 | 124.8 ± 16.7 | 2.520 | 0.012 |
ALB(g/L) | 38.2 ± 4.3 | 38.8 ± 4.1 | 37.4 ± 4.6 | 3.303 | 0.001 |
TP(g/L) | 66.4 ± 6.9 | 66.8 ± 6.8 | 65.6 ± 7.1 | 1.763 | 0.079 |
EF(%) | 65.7 (63.7,68.5) | 65.8 (63.7,68.5) | 65.6 (63.7,68.5) | 0.385 | 0.701 |
Calf circumference(cm) | 33.0 (31.0,36.0) | 34.0 (32.0,36.0) | 32.0 (30.0,34.0) | 7.534 | < 0.001 |
Maximum grip(kg) | |||||
 Male | 26.2 ± 7.9 | 29.1 ± 7.8 | 22.1 ± 6.1 | 8.074 | < 0.001 |
 Female | 20.6 ± 6.8 | 22.6 ± 6.7 | 15.9 ± 4.4 | 7.977 | < 0.001 |
6 m pace(m/s) | 0.7 ± 0.3 | 0.8 ± 0.3 | 0.6 ± 0.3 | 4.060 | < 0.001 |
SMM(kg) | |||||
 Male | 25.6 ± 4.6 | 28.2 ± 3.5 | 21.8 ± 3.0 | 15.702 | < 0.001 |
 Female | 20.5 ± 4.3 | 22.1 ± 3.8 | 16.7 ± 2.7 | 10.808 | < 0.001 |
ASMI(kg/m2) | |||||
 Male | 7.3 ± 1.2 | 8.0 ± 1.0 | 6.3 ± 0.7 | 16.164 | < 0.001 |
 Female | 6.3 ± 1.0 | 6.8 ± 0.8 | 5.2 ± 0.5 | 16.901 | < 0.001 |