Variables | Total (n = 650) | Before PSM | After PSM | ||||||
---|---|---|---|---|---|---|---|---|---|
DVT (n = 47) | Non-DVT (n = 603) | P | Std. Mean Diff | DVT (n = 47) | Non-DVT (n = 169) | P | Std. Mean Diff | ||
Age (years) | 76.3 (69.0–84.0) | 82.0 (72.0–86.0) | 72.0 (66.0–82.0) | 0.020 |  | 82.0 (72.0–86.0) | 75.0 (67.0–82.0) | 0.008 |  |
 60–74 | 278 (42.8%) | 13 (27.7%) | 265 (43.9%) | 0.030 | 0.974 | 13 (27.7%) | 80 (47.3%) | 0.016 | 0.881 |
 ≥ 75 | 323 (49.7%) | 28 (59.6%) | 295 (48.9%) | 0.497 | 28 (59.6%) | 78 (46.2%) | 0.492 | ||
BMI (kg/m2) | 22.7 (20.1–23.9) | 22.4 (20.9–23.6) | 22.2 (20.0–24.0) | 0.483 | 1.402 | 22.4 (20.9–23.6) | 22.4 (20.2–23.4) | 0.548 | 0.896 |
Sex (male) | 432 (66.5%) | 33 (70.2%) | 399 (66.2%) | 0.572 | 0.472 | 33 (70.2%) | 108 (63.9%) | 0.422 | 0.471 |
Underlying diseases | |||||||||
 COPD | 140 (21.5%) | 12 (25.5%) | 128 (21.2%) | 0.003 | 0.411 | 12 (25.5%) | 33 (19.5%) | 0.012 | 0.281 |
 Hypertension | 379 (58.3%) | 23 (48.9%) | 356 (59.0%) | 0.176 | 0.494 | 23 (48.9%) | 106 (62.7%) | 0.088 | 0.502 |
 Diabetes | 143 (22.0%) | 10 (21.3%) | 133 (22.1%) | 0.901 | 0.414 | 10 (21.3%) | 43 (25.4%) | 0.557 | 0.406 |
 Cardiogenic diseasesa | 206 (31.7%) | 10 (21.3%) | 196 (32.5%) | 0.111 | 0.465 | 10 (21.3%) | 55 (32.5%) | 0.136 | 0.448 |
 Renal system diseases | 58 (8.9%) | 2 (4.3%) | 56 (9.3%) | 0.421 | 0.283 | 2 (4.3%) | 18 (10.7%) | 0.258 | 0.188 |
 Gastrointestinal diseases | 26 (4.0%) | 0 | 26 (4.3%) | 0.247 | 0.196 | 0 | 12 (7.1%) | 0.073 | 0.000 |
 Peripheral vascular lesions | 19 (2.9%) | 0 | 19 (3.1%) | 0.387 | 0.169 | 0 | 3 (1.8%) | > 0.999 | 0.000 |
 Long-term indwelling catheterization | 57 (8.7%) | 4 (8.5%) | 53 (8.8%) | > 0.999 | 0.281 | 4 (8.5%) | 28 (16.6%) | 0.169 | 0.183 |
 Cerebrovascular diseasesb | 141 (21.7%) | 14 (29.8%) | 127 (21.1%) | 0.026 | 0.411 | 14 (29.8%) | 40 (23.7%) | 0.022 | 0.305 |
 Malignant tumors | 77 (11.8%) | 4 (8.5%) | 73 (12.1%) | 0.463 | 0.323 | 4 (8.5%) | 23 (13.6%) | 0.350 | 0.305 |
 Surgical history | 149 (22.9%) | 7 (14.9%) | 142 (23.5%) | 0.174 | 0.421 | 7 (14.9%) | 54 (32.0%) | 0.022 | 0.406 |
 Sepsis | 87 (13.4%) | 15 (31.9%) | 72 (11.9%) | 0.566 | 0.342 | 15 (31.9%) | 14 (8.3%) | 0.571 | 0.254 |
 Septic shock | 65 (10.0%) | 7 (14.9%) | 63 (10.4%) | 0.214 | 0.342 | 7 (14.9%) | 10 (5.9%) | > 0.999 | 0.130 |
 AKI | 109 (16.8%) | 6 (12.8%) | 103 (17.1%) | 0.508 | 0.374 | 6 (12.8%) | 23 (13.6%) | 0.953 | 0.363 |
Patient source | |||||||||
 Emergency room | 308 (47.4%) | 26 (55.3%) | 282 (46.8%) | 0.258 | 0.500 | 26 (55.3%) | 84 (49.7%) | 0.496 | 0.504 |
 General ward | 223 (34.3%) | 7 (14.9%) | 216 (35.8%) | 0.004 | 0.475 | 7 (14.9%) | 36 (21.3%) | 0.330 | 0.418 |
 Operating room | 96 (14.8%) | 12 (25.5%) | 84 (13.9%) | 0.031 | 0.355 | 12 (25.5%) | 38 (22.5%) | 0.661 | 0.457 |
 Othersc | 23 (3.5%) | 2 (4.3%) | 21 (3.5%) | 0.679 | 0.185 | 2 (4.3%) | 11 (6.5%) | 0.738 | 0.130 |
Reasons for admission to ICU | |||||||||
 Internal diseases | 447 (68.8%) | 18 (38.3%) | 429 (71.1%) | < 0.001 | 0.465 | 18 (38.3%) | 80 (47.3%) | 0.271 | 0.247 |
 Surgical diseases | 161 (24.8%) | 26 (55.3%) | 135 (22.4%) | < 0.001 | 0.432 | 26 (55.3%) | 87 (51.5%) | 0.641 | 0.098 |
 Traumatic injuries | 37 (5.7%) | 3 (6.4%) | 34 (5.6%) | 0.744 | 0.238 | 3 (6.4%) | 2 (1.2%) | 0.070 | 0.281 |
 Othersd | 5 (0.8%) | 0 | 5 (0.8%) | > 0.999 | 0.087 |  |  | – | – |
APACHE II | 21.0 (14.0–25.0) | 17.0 (12.0–26.0) | 20.0 (10.0–24.0) | 0.148 | 7.664 | 17.0 (12.0–26.0) | 19.0 (13.0–25.0) | 0.241 | 6.813 |
Biochemical indexes | |||||||||
 WBC (×109/L) | 12.2 (7.8–14.5) | 11.2 (7.9–14.0) | 10.6 (7.8–14.6) | 0.862 | 1.074 | 11.2 (7.9–14.0) | 10.1 (7.2–14.0) | 0.407 | 1.045 |
 Lactate (mmol/L) | 2.6 (1.3–3.1) | 1.8 (1.3–2.8) | 1.9 (1.3–3.2) | 0.641 | 2.320 | 1.8 (1.3–2.8) | 1.8 (1.3–3.2) | 0.613 | 1.492 |
 CRP (mg/L) | 71.5 (15.6–108.2) | 75.5 (17.5–142.4) | 48.5 (15.3–105.1) | 0.138 | 1.295 | 75.5 (17.5–142.4) | 42.5 (13.4–86.4) | 0.067 | 1.789 |
 APTT (s) | 36.3 (28.5–40.5) | 37.0 (32.5–44.4) | 33.3 (28.3–40.2) | 0.008 | 3.316 | 37.0 (32.5–44.4) | 32.2 (28.0–38.8) | 0.002 | 1.097 |
 INR | 1.3 (1.0–1.3) | 1.2 (1.04–1.32 | 1.1 (1.0–1.3) | 0.305 | 1.471 | 1.2 (1.04–1.32) | 1.1 (1.01–1.32) | 0.189 | 0.784 |
 D-dimer (mg/dl) | 4.8 (1.0–5.5) | 10.4 (6.0–16.7) | 2.3 (1.0–4.7) | < 0.001 | 2.809 | 10.4 (6.0–16.7) | 2.5 (0.9–5.3) | < 0.001 | 1.085 |
Treatments, n (%) | |||||||||
 Deep vein catheterization | 367 (56.5%) | 30 (63.8%) | 337 (55.9%) | 0.359 | 0.496 | 30 (63.8%) | 119 (70.4%) | 0.498 | 0.464 |
 Mechanical ventilation | 446 (68.6%) | 34 (72.3%) | 412 (68.3%) | 0.849 | 0.464 | 34 (72.3%) | 129 (76.3%) | 0.574 | 0.393 |
 Analgesic, sedative drugs or muscle relaxants | 390 (60.0%) | 35 (74.5%) | 355 (58.9%) | 0.036 | 0.490 | 35 (74.5%) | 109 (64.5%) | 0.047 | 0.393 |
 CRRT | 62 (9.5%) | 2 (4.3%) | 60 (10.0%) | 0.298 | 0.294 | 2 (4.3%) | 10 (5.9%) | > 0.999 | 0.222 |