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Table 1 Comparison of baseline data of the two groups before and after PSM

From: The risk factors for deep venous thrombosis in critically ill older adult patients: a subgroup analysis of a prospective, multicenter, observational study

Variables

Total (n = 650)

Before PSM

After PSM

DVT (n = 47)

Non-DVT (n = 603)

P

Std. Mean Diff

DVT (n = 47)

Non-DVT (n = 169)

P

Std. Mean Diff

Age (years)

76.3 (69.0–84.0)

82.0 (72.0–86.0)

72.0 (66.0–82.0)

0.020

 

82.0 (72.0–86.0)

75.0 (67.0–82.0)

0.008

 

 60–74

278 (42.8%)

13 (27.7%)

265 (43.9%)

0.030

0.974

13 (27.7%)

80 (47.3%)

0.016

0.881

 ≥ 75

323 (49.7%)

28 (59.6%)

295 (48.9%)

0.497

28 (59.6%)

78 (46.2%)

0.492

BMI (kg/m2)

22.7 (20.1–23.9)

22.4 (20.9–23.6)

22.2 (20.0–24.0)

0.483

1.402

22.4 (20.9–23.6)

22.4 (20.2–23.4)

0.548

0.896

Sex (male)

432 (66.5%)

33 (70.2%)

399 (66.2%)

0.572

0.472

33 (70.2%)

108 (63.9%)

0.422

0.471

Underlying diseases

 COPD

140 (21.5%)

12 (25.5%)

128 (21.2%)

0.003

0.411

12 (25.5%)

33 (19.5%)

0.012

0.281

 Hypertension

379 (58.3%)

23 (48.9%)

356 (59.0%)

0.176

0.494

23 (48.9%)

106 (62.7%)

0.088

0.502

 Diabetes

143 (22.0%)

10 (21.3%)

133 (22.1%)

0.901

0.414

10 (21.3%)

43 (25.4%)

0.557

0.406

 Cardiogenic diseasesa

206 (31.7%)

10 (21.3%)

196 (32.5%)

0.111

0.465

10 (21.3%)

55 (32.5%)

0.136

0.448

 Renal system diseases

58 (8.9%)

2 (4.3%)

56 (9.3%)

0.421

0.283

2 (4.3%)

18 (10.7%)

0.258

0.188

 Gastrointestinal diseases

26 (4.0%)

0

26 (4.3%)

0.247

0.196

0

12 (7.1%)

0.073

0.000

 Peripheral vascular lesions

19 (2.9%)

0

19 (3.1%)

0.387

0.169

0

3 (1.8%)

> 0.999

0.000

 Long-term indwelling catheterization

57 (8.7%)

4 (8.5%)

53 (8.8%)

> 0.999

0.281

4 (8.5%)

28 (16.6%)

0.169

0.183

 Cerebrovascular diseasesb

141 (21.7%)

14 (29.8%)

127 (21.1%)

0.026

0.411

14 (29.8%)

40 (23.7%)

0.022

0.305

 Malignant tumors

77 (11.8%)

4 (8.5%)

73 (12.1%)

0.463

0.323

4 (8.5%)

23 (13.6%)

0.350

0.305

 Surgical history

149 (22.9%)

7 (14.9%)

142 (23.5%)

0.174

0.421

7 (14.9%)

54 (32.0%)

0.022

0.406

 Sepsis

87 (13.4%)

15 (31.9%)

72 (11.9%)

0.566

0.342

15 (31.9%)

14 (8.3%)

0.571

0.254

 Septic shock

65 (10.0%)

7 (14.9%)

63 (10.4%)

0.214

0.342

7 (14.9%)

10 (5.9%)

> 0.999

0.130

 AKI

109 (16.8%)

6 (12.8%)

103 (17.1%)

0.508

0.374

6 (12.8%)

23 (13.6%)

0.953

0.363

Patient source

 Emergency room

308 (47.4%)

26 (55.3%)

282 (46.8%)

0.258

0.500

26 (55.3%)

84 (49.7%)

0.496

0.504

 General ward

223 (34.3%)

7 (14.9%)

216 (35.8%)

0.004

0.475

7 (14.9%)

36 (21.3%)

0.330

0.418

 Operating room

96 (14.8%)

12 (25.5%)

84 (13.9%)

0.031

0.355

12 (25.5%)

38 (22.5%)

0.661

0.457

 Othersc

23 (3.5%)

2 (4.3%)

21 (3.5%)

0.679

0.185

2 (4.3%)

11 (6.5%)

0.738

0.130

Reasons for admission to ICU

 Internal diseases

447 (68.8%)

18 (38.3%)

429 (71.1%)

< 0.001

0.465

18 (38.3%)

80 (47.3%)

0.271

0.247

 Surgical diseases

161 (24.8%)

26 (55.3%)

135 (22.4%)

< 0.001

0.432

26 (55.3%)

87 (51.5%)

0.641

0.098

 Traumatic injuries

37 (5.7%)

3 (6.4%)

34 (5.6%)

0.744

0.238

3 (6.4%)

2 (1.2%)

0.070

0.281

 Othersd

5 (0.8%)

0

5 (0.8%)

> 0.999

0.087

  

–

–

APACHE II

21.0 (14.0–25.0)

17.0 (12.0–26.0)

20.0 (10.0–24.0)

0.148

7.664

17.0 (12.0–26.0)

19.0 (13.0–25.0)

0.241

6.813

Biochemical indexes

 WBC (×109/L)

12.2 (7.8–14.5)

11.2 (7.9–14.0)

10.6 (7.8–14.6)

0.862

1.074

11.2 (7.9–14.0)

10.1 (7.2–14.0)

0.407

1.045

 Lactate (mmol/L)

2.6 (1.3–3.1)

1.8 (1.3–2.8)

1.9 (1.3–3.2)

0.641

2.320

1.8 (1.3–2.8)

1.8 (1.3–3.2)

0.613

1.492

 CRP (mg/L)

71.5 (15.6–108.2)

75.5 (17.5–142.4)

48.5 (15.3–105.1)

0.138

1.295

75.5 (17.5–142.4)

42.5 (13.4–86.4)

0.067

1.789

 APTT (s)

36.3 (28.5–40.5)

37.0 (32.5–44.4)

33.3 (28.3–40.2)

0.008

3.316

37.0 (32.5–44.4)

32.2 (28.0–38.8)

0.002

1.097

 INR

1.3 (1.0–1.3)

1.2 (1.04–1.32

1.1 (1.0–1.3)

0.305

1.471

1.2 (1.04–1.32)

1.1 (1.01–1.32)

0.189

0.784

 D-dimer (mg/dl)

4.8 (1.0–5.5)

10.4 (6.0–16.7)

2.3 (1.0–4.7)

< 0.001

2.809

10.4 (6.0–16.7)

2.5 (0.9–5.3)

< 0.001

1.085

Treatments, n (%)

 Deep vein catheterization

367 (56.5%)

30 (63.8%)

337 (55.9%)

0.359

0.496

30 (63.8%)

119 (70.4%)

0.498

0.464

 Mechanical ventilation

446 (68.6%)

34 (72.3%)

412 (68.3%)

0.849

0.464

34 (72.3%)

129 (76.3%)

0.574

0.393

 Analgesic, sedative drugs or muscle relaxants

390 (60.0%)

35 (74.5%)

355 (58.9%)

0.036

0.490

35 (74.5%)

109 (64.5%)

0.047

0.393

 CRRT

62 (9.5%)

2 (4.3%)

60 (10.0%)

0.298

0.294

2 (4.3%)

10 (5.9%)

> 0.999

0.222

  1. PSM Propensity score matching, BMI Body mass index, COPD Chronic obstructive pulmonary disease, AKI Acute kidney injury, ICU Intensive care unit, APACHE II Acute Physiology and Chronic Health Evaluation II, WBC White blood cells, CRP C-reactive protein, APTT Activated partial thromboplastin time, INR International normalized ratio, CRRT Continuous renal replacement therapy
  2. aIncluding coronary artery disease, arrhythmia, and heart failure
  3. bIncluding ischemic stroke and cerebral hemorrhage disease
  4. cIncluding other ICU, inpatient beds, outpatient clinics
  5. dIncluding various types of drug poisoning