Table 4 Sex stratified associations between individual symptom, symptoms combination patterns and counts on frailty

Individual symptom

Chronic pain

  No

1.00

-

1.00

-

1.00

-

1.00

-

  Yes

2.24(1.37,3.68)

0.001

2.03(1.11,3.71)

0.021

1.18(0.63,2.22)

0.610

1.07(0.51,2.25)

0.865

Depressive symptoms

  No

1.00

-

1.00

-

1.00

-

1.00

-

  Yes

3.22(1.53,6.77)

0.002

2.98(1.16,7,70)

0.024

1.44(0.65,3.18)

0.374

1.75(0.71,4.32)

0.222

Poor sleep quality

  No

1.00

-

1.00

-

1.00

-

1.00

-

  Yes

1.91(1.19,3.07)

0.007

1.64(0.92,2.93)

0.091

1.97(0.96,4.05)

0.065

1.44(0.63,3.32)

0.392

symptom combination patterns

  No symptom

1.00

-

1.00

-

1.00

-

1.00

-

  Chronic pain only

2.66(1.22,5.83)

0.014

2.59(1.01,6.61)

0.047

0.56(0.11,2.95)

0.496

0.59(0.09,3.72)

0.571

  Depressive symptoms only

2.04(0.18,23.4)

0.567

1.73(0.12,25.43)

0.689

2.25(0.18,27.96)

0.528

1.44(0.09,22.62)

0.797

  Poor sleep quality only

1.75(0.93,3.28)

0.081

1.47(0.68,3.18)

0.325

1.69(0.66,4.31)

0.274

1.23(0.41,3.69)

0.712

  Chronic pain and depressive symptoms

2.04(0.18,23.41)

0.567

1.08(0.03,38.92)

0.967

-

1.000

-

1.000

  Poor sleep quality and depressive symptoms

5.71(1.67,19.51)

0.005

6.92(1.48,32.42)

0.014

2.42(0.73,8.02)

0.147

2.40(0.62,9.33)

0.207

  Poor sleep quality and chronic pain

2.94(1.39,6.20)

0.005

2.48(1.02,5.98)

0.044

2.25(0.85,5.95)

0.102

1.45(0.47,4.54)

0.520

  Poor sleep quality and chronic pain and depressive symptoms

7.34(2.26,23.84)

0.001

4.50(1.08,18.73)

0.039

1.93(0.41,9.13)

0.408

1.76(0.29,10.72)

0.542

Symptom counts

  0

1.00

-

1.00

-

1.00

-

1.00

-

  1

1.99(1.13,3.52)

0.018

1.78(0.90,3.52)

0.097

1.43(0.58,3.56)

0.439

1.11(0.39,3.19)

0.849

  2

3.32(1.68,6.53)

0.001

2.90(1.29,6.52)

0.010

2.25(0.90,5.62)

0.082

1.68(0.58,4.87)

0.339

  3

7.34(2.26,23.84)

0.001

4.46(1.08,18.38)

0.039

1.93(0.41,9.13)

0.408

1.80(0.30,10.94)

0.525