Certainty assessment | Certainty | Importance |
---|
№ of studies | Study design | Risk of bias | Inconsistency | Indirectness | Imprecision | Other considerations |
---|
2 | observational studies | not serious | not serious | not serious | seriousa | none | ⨁⨁⨁◯ Moderate | CRITICAL |
- aOne study had a large sample size (n = 2638), but consisted of unbalanced exposure (n = 2199, 83.4%) versus non-exposure groups (n = 169, 6.41%) [54]. Although the other study had a large sample size, the number of exposed versus unexposed participants was unclear [53]