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Table 2 Intervention, control, and intragroup effects and statistical significance within included studies. Data are expressed as mean (standard deviation), unless otherwise stated

From: Medium-chain triglycerides may improve memory in non-demented older adults: a systematic review of randomized controlled trials

Study, year

Outcome

Control group

Intervention group

Intergroup

P-value

Pre-intervention, n

Post-intervention, n

P-value

Pre-intervention, n

Post-intervention, n

P-value

Mutoh,2022 [22]

LM-IA

13.3 (3.5)

14.9 (3.8)

0.003

11.3 (4.1)

14.1 (4.1)

 < 0.001

0.078

LM-IB

10.4 (3.5)

12.1 (2.9)

0.002

9.5 (3.1)

10.8 (3.5)

0.013

0.146

LM-IIA

10 (3.8)

12.2 (4.1)

 < 0.001

8.7 (4.6)

11.2 (5.1)

 < 0.001

0.285

LM-IIB

8.3 (3.7)

10.2 (3.9)

 < 0.001

7.5 (3.4)

9.9 (3.8)

 < 0.001

0.552

Yomogida, 2021 [21]

Working memory (N-back test)

NA

73.39 (3.57)

NA

NA

77.86

NA

NA

Abe, 2020 [20]

MMSE

17

16.3

NA

17.5

21

NA

NA

NM

30.9

27.5

NA

31

33.7

NA

 

O’neill, 2019 [19]

VRM task

NA

NA

NA

NA

NA

NA

NA

SWM task

NA

NA

NA

NA

NA

NA

NA

Abe, 2017 [18]

MMSE

1.8 (1.4)

1.7 (1.4)

NA

1.3 (1.3)

1.5 (1.3)

NA

NA

NM

7.1 (2.8)

6 (3.3)

 < 0.05

4.7 (2.4)

6.7 (2)

 < 0.001

0.001

Ota, 2016 [16]

Digit-span test

NA

9.6 (3)

NA

NA

9.9 (2.9)

NA

0.41

Visual memory span test

NA

12 (2)

NA

NA

12.2 (2.3)

NA

0.64

Letter-number sequencing test

NA

11.8 (2.3)

NA

NA

11.8 (1.6)

NA

0.75

  1. LM-I Logical memory-immediate recall, LM-II Logical memory-delayed recall, MMSE Mini-mental state exam, NA Not available, NM Nishimura geriatric rating scale for mental status, SWM Spatial working memory, VRM Verbal recognition memory