Table 3 Subgroup analysis for the criterion validity of the instrument
Group | Cutoff | Youden Index | % (95% Confidence Interval) | Likelihood Ratio | ||
|---|---|---|---|---|---|---|
(95% Confidence Interval) | ||||||
sensitivity | specificity | Positive | Negative | |||
PN (n = 312) | 0.97 | 0.23 | 90.0 (75.4—96.7) | 32.7 (27.2—38.7) | 1.34 (1.17—1.53) | 0.31 (0.12—0.79) |
9.03 | 0.38 (max) | 50.0 (34.1—65.9) | 87.5 (82.8—91.1) | 4.00 (2.57—6.22) | 0.57 (0.42—0.78) | |
10.26 | 0.35 | 45.0 (29.6—61.3) | 90.4 (86.2—93.5) | 4.71 (2.85—7.77) | 0.60 (0.46—0.81) | |
PNN (n = 467) | 2.27 | 0.14 | 90.0 (79.9—95.5) | 23.7 (19.6—28.2) | 1.18 (1.07—1.30) | 0.42 (0.21— 0.87) |
12.37 | 0.54 (max) | 65.7 (53.3—76.4) | 88.4 (84.8—91.3) | 5.67 (4.12—7.81) | 0.39 (0.28—0.54) | |
13.76 | 0.52 | 61.4 (49.0—72.5) | 90.7 (87.3—93.3) | 6.60 (4.60—9.43) | 0.43 (0.32—0.57) | |
Dementia (n = 47) | 4.20 | 0.04 | 88.9 (69.7—97.1) | 15.0 (4.0—38.9) | 1.05 (0.83—1.53) | 0.74 (0.15—3.75) |
22.00 | 0.38 | 48.1 (29.1—67.6) | 90.0 (66.9—98.2) | 4.81(1.22—18.98) | 0.58 (0.40—0.84) | |
25.00 | 0.4 (max) | 44.4 (26.0—64.4) | 95.0 (73.1—99.7) | 8.88 (1.26—62.87) | 0.58 (0.42—0.82) | |
Non-dementia (n = 732) | 2.05 | 0.2 | 89.2 (79.9—94.6) | 30.7 (27.2—34.4) | 1.29 (1.17—1.40) | 0.35 (0.19— 0.66) |
11.14 | 0.42 (max) | 55.4 (44.1—66.2) | 86.9 (84.0—89.4) | 4.23 (3.21—5.58) | 0.51 (0.40—0.65) | |
11.82 | 0.38 | 48.2 (37.2—59.4) | 90.1 (87.5—92.2) | 4.89 (3.54—6.75) | 0.57 (0.47—0.83) | |
Depression (n = 32) | 9.27 | 0.01 | 66.7 (24.1—94.0) | 34.6 (17.9—55.6) | 1.02 (0.54—1.92) | 0.96 (0.27—3.44) |
23.13 | 0.35 (max) | 50.0 (13.9—86.1) | 84.6 (64.3—95.0) | 3.25 (0.97—10.85) | 0.59 (0.26—1.33) | |
27.99 | 0.01 | 16.7 (00.8—63.5) | 84.6 (64.2—95.0) | 1.08 (0.15—8.03) | 0.98 (0.68—1.43) | |
Non-depression (n = 747) | 2.05 | 0.22 | 91.3 (83.8—95.7) | 30.9 (27.4—34.7) | 1.32 (1.22—1.43) | 0.28 (0.15—0.53) |
11.14 | 0.5 (max) | 62.5 (52.4—71.6) | 87.1 (84.2—89.5) | 4.84 (3.77—6.22) | 0.43 (0.34—0.55) | |
11.82 | 0.47 | 56.7 (46.7—66.3) | 90.0 (87.4—92.2) | 5.70 (4.28—7.59) | 0.98 (0.68—1.43) | |