Association between environmental exposure to perchlorate, nitrate, and thiocyanate and serum α-Klotho levels among adults from the National Health and nutrition examination survey (2007–2014)

Table 3 Association between urinary thiocyanate levels and α-Klotho levels stratified by subgroup and interaction analyses (n = 4.875)

Subgroups	Total (n = 4.875)	β (95% CI)	P	Interaction P
Mexican American	772	0.00 (− 0.01 − 0.01)	0.86	0.68
Other Hispanic	525	−0.01 (− 0.02–0.01)	0.49
Non-Hispanic White	2324	–0.01 (−0.01 to − 0.00)	0.002
Non-Hispanic Black	948	−0.00 (− 0.01–0.00)	0.22
Other races	306	−0.01 (− 0.03 to − 0.00)	0.02
Male	2417	− 0.00 (− 0.01–0.00)	0.18	0.003
Female	2458	−0.01 (− 0.02 to − 0.01)	< 0.0001	0.003
< 65 years	3446	− 0.01 (− 0.01 to − 0.00)	< 0.0001	0.40
≥65 years	1429	− 0.00 (− 0.01 − 0.01)	0.72	0.40
Obesity	2915	–0.01 (− 0.01 to − 0.00)	0.0001	0.16
Non-obesity	1960	− 0.00 (− 0.01–0.00)	0.09	0.16
≥12 alcoholic drinks/year	3349	− 0.01 (− 0.01 to − 0.00)	0.0004	0.73
< 12 alcoholic drinks/year	1319	− 0.01 (− 0.01 to − 0.00)	0.03	0.73
Vigorous activity	858	− 0.00 (− 0.01–0.00)	0.38	0.27
Moderate activity	1069	− 0.01 (− 0.02 to − 0.00)	0.003
Inactive	2948	− 0.01 (− 0.01 to − 0.00)	0.0009
≥100 cigarettes in lifetime	2449	− 0.01 (− 0.01 to − 0.00)	0.0021	0.05
< 100 cigarettes in lifetime	2462	− 0.01 (− 0.02 to − 0.00)	0.0023	0.05

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