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Table 3 Critical quality appraisal for included meta-analyses according to AMSTAR 2 [41]

From: Efficacy and safety of adrenergic alpha-1 receptor antagonists in older adults: a systematic review and meta-analysis supporting the development of recommendations to reduce potentially inappropriate prescribing

Authors (Year)

PICO scheme used?

Review methods prior to conduct?

Explanation for inclusion of study designs?

Comprehensive literature search?

 ≥ 2 independent reviewers performed study selection?

 ≥ 2 independent reviewers performed data extraction?

List of excl. studies?

Detailed prescription of incl. studies?

RoB assessment?

Sources of funding of incl. studies mentioned?

Appropriate methods for meta-analysis?

Influence of RoB in meta-analysis?

RoB considered in interpretation/discussion of results?

Explanation for heterogeneity?

Publication bias considered?

Funding and conflict of interest stated?

Buzelin et al. (1997) [57]

N

N

N

N

N

N

N

N

N

N

U

N

N

N

N

N

Lowe (1994) [58]

N

N

N

N

N

N

N

N

N

N

U

N

N

N

N

Y

Chapple et al. (1997) [59]

N

N

N

N

N

N

N

N

N

N

U

N

N

N

N

Y

  1. Y Yes, N No, U Unclear, RoB Risk of Bias