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Table 1 Baseline characteristics of the study cohort at Frail-VIG0 time point (i.e., one month before admission)

From: Transitions between degrees of multidimensional frailty among older people admitted to intermediate care: a multicentre prospective study

Variable

All

n = 483

Frailty status a

p-value

No

frailty

n = 115

Mild

frailty

n = 187

Intermediate frailty

n = 122

Advanced frailty

n = 59

Age, mean (SD)

81.28(10.21)

79.97(9.22)

80.74(10.90)

82.46(10.58)

83.06(8.63)

0.120

Sex, women (%)

260(53.80)

64(55.65)

101(54.01)

64(52.46)

31(52.54)

0.962

Usual habitat(%)

 with family

317(65.63)

74(64.34)

120(64.17)

86(70.49)

37(62.71)

0.623

 with caregiver

23(4.76)

1(0.86)

7(3.74)

8(6.56)

7(3.74)

0.008

 Alone

116(24.02)

40(34.78)

56(29.95)

16(13.11)

4(6.77)

 < 0.001

 Nursing Home

27(5.59)

0(0.00)

4(2.14)

12(9.83)

11(18.64)

 < 0.001

Unit of income (%)

 Palliative care unit

190(39.34)

40(34.78)

83(44.39)

42(34.43)

25(42.37)

0.216

 Rehabilitation unit

113(23.40)

40(34.78)

40(21.39)

25(20.49)

8(13.56)

0.006

 Psicogeriatric unit

79(16.36)

6(5.21)

23(12.30)

35(28.69)

15(25.42)

 < 0.001

 Hospital-at-home unit

49(10.14)

23(20.00)

20(10.70)

5(4.10)

1(1.69)

 < 0.001

 HSJ

52(10.76)

6(5.22)

21(11.23)

15(12.30)

10(16.95)

0.095

 Stay average. Median (IQR)

20(25)

21(26)

21(28)

21(25)

14(20)

0.113

Individual variablesb

 IADLs (0–3), mean (SD)

1.35 (1.28)

0.17 (0.46)

1.00 (1.10)

2.36 (0.88)

2.76 (0.54)

 < 0.001

 Barthel index (0–100), mean (SD)

76.84(25.64)

91.31(17.93)

86.03(15.86)

64.19(25.54)

42.26(25.23)

 < 0.001

 Malnutrition (%)

135(27.85)

17(14.78)

47(25.13)

39(31.98)

33(55.93)

 < 0.001

 Cognitive impairment (%)

158(32.71)

2(1.74)

41(221.93)

65(53.28)

50(84.75)

 < 0.001

 Depressive syndrome (%)

139(28.78)

11(9.57)

44(23.53)

53(43.44)

31(52.54)

 < 0.001

 Insomnia/anxiety (%)

225(46.58)

24(20.87)

85(45.45)

76(62.30)

40(67.80)

 < 0.001

 Social vulnerability (%)

74(15.32)

4(3.48)

29(15.51)

23(18.85)

18(30.51)

 < 0.001

 Delirium (%)

67(13.87)

0(0.00)

10(5.35)

29(23.77)

28(47.46)

 < 0.001

 Falls (%)

99(20.49)

6(6.06)

39(39.39)

37(37.37)

17(17.18)

0.004

 Ulcers (%)

51(10.55)

6(5.22)

16(8.56)

16(13.11)

13(22.03)

0.004

 Polypharmacy (%)

389(80.54)

68(59.13)

160(85.56)

104(85.25)

57(96.61)

 < 0.001

 Dysphagia (%)

76(15.73)

2(1.74)

16(8.56)

20(16.39)

38(64.41)

 < 0.001

 Pain (%)

117(24.22)

8(6.96)

58(31.02)

32(26.23)

19(32.20)

 < 0.001

 Dyspnea (%)

46(9.52)

1(0.87)

15(8.02)

19(15.57)

11(18.64)

 < 0.001

 Cancer (%)

121(25.05)

24(20.87)

60(32.08)

23(18.85)

14(23.73)

0.036

 Chronic respiratory disease(%)

110(22.77)

22(19.13)

41(21.93)

36(29.51)

11(18.64)

0.198

 Chronic Cardiac disease (%)

217(44.92)

34(29.57)

75(40.11)

70(57.38)

38(64.41)

 < 0.001

 Chronic Neurological disease (%)

65(13.46)

7(6.09)

20(10.70)

21(17.21)

17(28.81)

 < 0.001

 Chronic Digestive disease (%)

36(7.45)

2(1.74)

18(9.63)

8(6.56)

8(13.56)

0.018

 Chronic Renal disease (%)

189(39.13)

25(21.74)

70(37.43)

56(45.90)

38(64.41)

 < 0.001

  1. aNo frailty (Frail-VIG index score < 0.2), mild frailty (Frail-VIG index score 0.2–0.35), moderate frailty (Frail-VIG index score 0.36–0.5), and advanced frailty (Frail-VIG index score > 0.5)
  2. bCriteria for clinical conditions are defined in the Supplementary Appendix
  3. IADLs Instrumental of activities of daily living (adapted from the Lawto-Brody scale, as described previously) [25]. IQR Interquartile range (25th and 75th percentiles), SD Standard deviation