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Table 4 Genotyping

From: A clinicopathological study of selected cognitive impairment cases in Lothian, Scotland: enhanced CJD surveillance in the 65 + population group

  N %
Genotyping (PRNP-Codon 129)
Study consented 25 83%
Of whom tested 25 100%
  MM 8 32%
  MV 13 52%
  VV 4 16%
Duration of illness (from the onset of symptoms to censor date/death)
  MM Mean = 8.3 years (1.1 – 16.6 years, std dev 5.5)
  MV Mean = 10.4 years (4.1 – 17.4 years, std dev 4.6)
  VV Mean = 11.3 years (6.6 – 16.6 years, std dev 4.7)
Age at onset of symptoms
  MM Mean = 64 years (56 – 79 years, std dev 7.4)
  MV Mean = 65 years (53 – 78 years, std dev 7.8)
  VV Mean = 63 years (56 – 69 years, std dev 5.4)
Gender
  MM Male = 5 (63%), Female = 3 (37%)
  MV Male = 8 (62%), Female = 5 (38%)
  VV Male = 2 (50%), Female = 2 (50%)
  Not known Male = 4 (80%), Female = 1 (20%)
  1. Note: Std dev is standard deviation