Prevalence of potentially inappropriate medications among old people with major neurocognitive disorder in 2012 and 2017

Table 3 Simple and multiple logistic regression analysis of factors associated with PIM use

PIM	Simple OR	95% CI	P-value	Multiple OR	95% CI	P-value
Female sex^a	1.020	0.967–1.076	0.459	0.991	0.935–1.050	0.758
Older age	0.979	0.975–0.983	< 0.001	0.968	0.964–0.972	< 0.001
Multi-dispensed drugs	1.768	1.675–1.867	< 0.001	2.052	1.932–2.179	< 0.001
Baseline MMSE-score^b	0.987	0.982–0.993	< 0.001	0.992	0.987–0.998	0.007
Year 2017 ^c	0.687	0.652–0.724	< 0.001	0.652	0.617–0.690	< 0.001
Vascular dementia^d	1.145	1.082–1.212	< 0.001	1.095	1.030–1.164	0.003
Dementia with Lewy bodies and Parkinson dementia^d	1.755	1.580–1.950	< 0.001	1.567	1.401–1.753	< 0.001
Frontotemporal dementia^d	1.465	1.241–1.730	< 0.001	1.292	1.081–1.544	0.005

CI confidence interval, MMSE Mini Mental State Examination score, OR odds ratio, PIM potentially inappropriate medication. PIM use was the dependent variable. Sex, age, multi-dispensed drugs, MMSE, year of investigation and type of major neurocognitive disorder were independent variables
^aData were missing for 6 individuals
^bData were missing for 1,457 individuals
^cReference category year 2012
^dReference category Alzheimer’s disease (early and late onset)

ISSN: 1471-2318