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Table 1 Characteristics of robust/prefrail and frail participants based on the Study of Osteoporotic Fractures (SOF) index, the Fatigue, Resistance, Ambulation, Illness and Loss of weight (FRAIL) index and the Cardiovascular Health Study (CHS) index

From: Predicting frailty in older adults using vocal biomarkers: a cross-sectional study

 

SOF

FRAIL

CHS (Fried's)

Robust/ prefrail

Frail

 

Robust/ prefrail

Frail

 

Robust/ prefrail

Frail

N = 277

N

(%)

N

(%)

P value†

N

(%)

N

(%)

P value†

N

(%)

N

(%)

P value†

Women (N = 175, 63.2%)

145

(63.6)

30

(61.2)

0.75

143

(64.1)

32

(59.3)

0.53

138

(62.7)

37

(64.9)

0.88

Age (years)a

73.8

 ± 6.7

76.6

 ± 8.3

0.01

73.8

 ± 6.8

76.4

 ± 8.0

0.02

73.6

 ± 6.7

76.9

 ± 8.1

 < 0.01

Body weight (kg)a

59.6

 ± 10.5

50.7

 ± 8.4

 < 0.01

59.1

 ± 10.3

53.5

 ± 11.1

 < 0.01

59.2

 ± 9.6

53.6

 ± 13.1

 < 0.01

BMI (kg/m2)a

24.4

 ± 4.2

21.6

 ± 3.0

 < 0.01

24.2

 ± 4.1

22.6

 ± 4.1

0.01

24.1

 ± 3.8

23.0

 ± 5.1

0.07

Weight loss

24

(10.5)

34

(69.4)

 < 0.01

26

(11.7)

32

(59.3)

 < 0.01

33

(15.0)

25

(43.9)

 < 0.01

Exhaustion

23

(10.1)

43

(87.8)

 < 0.01

25

(11.2)

41

(75.9)

 < 0.01

26

(11.8)

40

(70.2)

 < 0.01

Low grip strength

102

(44.7)

30

(61.2)

 < 0.01

95

(42.6)

37

(68.5)

 < 0.01

81

(36.8)

51

(89.5)

 < 0.01

Slow gait speed

64

(28.1)

35

(71.4)

 < 0.01

56

(25.1)

43

(79.6)

 < 0.01

46

(20.9)

53

(93.0)

 < 0.01

Cannot complete 5 times CST

69

(30.3)

40

(81.6)

 < 0.01

63

(28.3)

46

(85.2)

 < 0.01

67

(30.5)

42

(73.7)

 < 0.01

ADL impairment

16

(7.0)

14

(28.6)

 < 0.01

10

(4.5)

20

(37.0)

 < 0.01

3

(1.4)

27

(47.4)

 < 0.01

Polypharmacy (> 8 kinds)

11

(4.8)

16

(32.7)

 < 0.01

3

(1.4)

24

(44.4)

 < 0.01

7

(3.2)

20

(35.1)

 < 0.01

Malnutrition

77

(33.8)

29

(59.2)

 < 0.01

71

(31.8)

35

(64.8)

 < 0.01

71

(32.3)

35

(61.4)

 < 0.01

ED visits or hospital admission in recent one year

12

(5.3)

12

(24.5)

 < 0.01

10

(4.5)

14

(25.9)

 < 0.01

5

(2.3)

19

(33.3)

 < 0.01

  1. † Chi square/ Fisher’s test or ANOVA test. aMean ± standard deviation
  2. SOF the Study of Osteoporotic Fractures index, FRAIL the Fatigue, Resistance, Ambulation, Illness and Loss of weight index, CHS the Cardiovascular Health Study index, BMI body mass index, CST chair stand test, ADL activity of daily life, ED emergency department