Table 1 Subject Characteristics

Age, years old

67.3 ± 6.4

69.2 ± 6.9

68.0 ± 6.6

< 0.005**

0.99

 Male

275 (62.2%)

167 (37.8%)

442 (60.7%)

 Female

178 (62.2%)

108 (37.8%)

286 (29.3%)

Body Mass Index, kg/m²

23.1 ± 7.6

23.9 ± 3.8

23.9 ± 6.2

0.063

 Weight, kg

61.8 ± 11.8

62.8 ± 10.6

62.1 ± 11.3

 Height, cm

160.6 ± 10.1

161.7 ± 6.5

161.0 ± 8.7

< 0.005*

 Score 0

180 (74.4%)

62 (25.6%)

242 (33.2%)

 Score 1-2

211 (61.5%)

132 (38.5%)

343 (47.1%)

 Score 3-4

45 (48.4%)

48 (51.6%)

93 (12.8%)

 Score > 5

17 (34%)

33 (66%)

50 (6.9%)

< 0.005* (3.5; 2.28-5.38)

 No comorbidity

136 (81.9%)

30 (18.1) %

166 (22.8%)

 At least one

317 (56.4%)

245 (43.6%)

563 (77.2%)

< 0.005* (3.43; 2.46-4.78)

 Surgical

238 (78%)

67 (22%)

305 (41.9%)

 Medical

215 (50.8%)

208 (49.2%)

423 (58.1%)

< 0.005* (10.48; 6.80-16.15)

 No

246 (89.8%)

28 (10.2%)

274 (37.6%)

 Yes

207 (45.6%)

247 (54.4%)

454 (62.4%)

< 0.005* (12.40; 8.51-18.07)

 No

400 (79.4%)

104 (20.6%)

504 (69.2%)

 Yes

53 (23.7%)

171 (76.3%)

224 (30.8%)

< 0.005* (3.5; 2.28-5.381)

 No

384 (85.3%)

66 (14.7%)

405 (55.6%)

 Yes

69 (24.8%)

209 (75.2%)

278 (38.2%)

< 0.005* (17.62; 12.08-25.69)

 Non-COVID

327 (74.5%)

112 (25.5%)

439 (60.3%)

 COVID-19

126 (43.6%)

163 (56.4%)

289 (39.7%)

MSOFA Score initial

3.8 ± 2.9

7.0 ± 3.8

5.1 ± 3.7

< 0.005**

MSOFA Score Day-30

1.8 ± 2.3

9.2 ± 6.5

4.8 ± 5.8

< 0.005**

Length of stay in ICU, days

5.9 ± 6.5

8.2 ± 7.6

6.9 ± 7.0

< 0.005**

Duration of mechanical ventilation, days

2.4 ± 5.3

6.3 ± 7.1

4.0 ± 6.4

< 0.005**