Worsening functional status in nephrogeriatrics needs to be accounted for when clinically assessing CKD advancement in addition to GFR; supporting evidence based on the practical application of theoretical modelling

Table 1 The results of the theoretical model describing the interrelationships between CKD and the patient's age, comorbidity, the number of medications taken and the functional status measured using the IADL, Tinetti, and Barthel tests

Dependent variable	Impact direction	Independent variable	β	B	S.E	Z	P	R²
CKD	< –-	Comorbidities	,55	,33	,05	6,66	***	0,30
CKD	< –-	Age	,30	,06	,01	5,41	***	0,09
CKD	< –-	Medication	,19	,093	,03	2,68	***	0,03
GFR	< –-	CKD	-,91	-20,47	1,01	-20,14	***	0,83
Urea	< –-	CKD	,92	29,65	1,47	20,09	***	0,86
Creatinine	< –-	CKD	,91	1,00			***	0,82
IADL	< –-	CKD	-,49	-,48	,060	-8,11	***	0,24
Barthel	< –-	CKD	-,40	-3,14	,47	-6,65	***	0,16
Tinetti	< –-	CKD	-,71	-2,96	,20	-14,49	***	0,51

β - Beta standarised coefficient, B - Beta unstandarised coefficient (in units of measurements), S.E.- Standard error of B, Z - Value of Z distribution statistic, p - significance
R.² - coefficient of determination
^*** p < 0.001
^** p < 0.01
^* p < 0.05

ISSN: 1471-2318