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Table 1 Characteristics of REGARDS study participants included in the current analysis

From: Frailty, gaps in care coordination, and preventable adverse events

Characteristics

Overall

Not frail

Intermediate-frail

Frail

P-value

(n = 5024)

(n = 2398)

(n = 2436)

(n = 190)

Demographic characteristics

 Age, years

73.5 ± 6.1

72.9 ± 5.8

74.0 ± 6.2

74.2 ± 6.8

 < 0.001

 Female

2799 (55.7)

1269 (52.9)

1402 (57.6)

128 (67.4)

 < 0.001

 Black

1615 (32.2)

763 (31.8)

784 (32.2)

68 (35.8)

0.528

 Annual income < $25,000

937 (19.8)

359 (15.8)

512 (22.4)

66 (38.6)

 < 0.001

 Less than high school education

254 (5.1)

94 (3.9)

137 (5.6)

23 (12.1)

 < 0.001

 Marital status, Married

2972 (59.3)

1510 (63.2)

1378 (56.7)

84 (44.2)

 < 0.001

 Geographic region of residencea

  Stroke belt

1602 (31.9)

745 (31.1)

799 (32.8)

58 (30.5)

0.579

  Stroke buckle

1079 (21.5)

535 (22.3)

503 (20.7)

41 (21.6)

  Other US regions

2343 (46.6)

1118 (46.6)

1134 (46.6)

91 (47.9)

 Rural areab

499 (11.0)

229 (10.6)

252 (11.4)

18 (9.9)

0.604

Clinical characteristics

 Hypertension

3461 (68.9)

1591 (66.4)

1718 (70.5)

152 (80.0)

 < 0.001

 Hyperlipidemia

3102 (63.8)

1463 (62.7)

1508 (64.1)

131 (72.0)

0.039

 Diabetes

1240 (25.5)

525 (22.5)

643 (27.4)

72 (39.1)

 < 0.001

 History of myocardial infarction

746 (15.4)

291 (12.5)

414 (17.6)

41 (22.8)

 < 0.001

 Prior coronary revascularization

796 (15.9)

333 (13.9)

425 (17.5)

38 (20.0)

0.001

 History of stroke

285 (5.7)

97 (4.1)

165 (6.8)

23 (12.2)

 < 0.001

 Chronic kidney disease

1885 (40.3)

828 (36.5)

965 (43.1)

92 (52.9)

 < 0.001

 Atrial fibrillation

581 (12.1)

237 (10.3)

315 (13.6)

29 (16.2)

0.001

 Self-rated health

  Excellent

652 (13.0)

412 (17.3)

232 (9.6)

8 (4.2)

 < 0.001

  Very good/good

3684 (73.6)

1807 (75.6)

1773 (73.1)

104 (54.7)

  Fair/poor

669 (13.4)

170 (7.1)

421 (17.4)

78 (41.1)

 Self-reported disability

  Disability in ≥ 1 ADL task

556 (11.1)

113 (4.7)

371 (15.3)

72 (37.9)

 < 0.001

  Disability in ≥ 1 IADL task

1596 (31.8)

489 (20.4)

976 (40.1)

131 (69.0)

 < 0.001

Frailty indicators

 Low BMI

40 (0.8)

0 (0.0)

32 (1.3)

8 (4.2)

 < 0.001

 Exhaustion

611 (12.3)

0 (0.0)

479 (19.8)

132 (69.5)

 < 0.001

 Slow walk

1012 (20.5)

0 (0.0)

864 (36.1)

148 (77.9)

 < 0.001

 Weakness

920 (20.1)

0 (0.0)

784 (36.2)

136 (85.5)

 < 0.001

 History of falls

1156 (23.1)

0 (0.0)

990 (40.8)

166 (87.8)

 < 0.001

Ambulatory utilization

 Number of ambulatory visits in the past 12 months, median (25th, 75th percentiles)

5 (3,8)

5 (3,7)

5 (3,8)

6 (4,10)

 < 0.001

 Number of ambulatory providers in the past 12 months, median (25th, 75th percentiles)

3 (2,4)

3 (2,4)

3 (2,4)

3 (3,5)

 < 0.001

  1. Values are mean ± standard deviation or frequencies (%)
  2. ADL Activities of daily living, IADL Instrumental activities of daily living, BMI body mass index
  3. a Stroke buckle includes coastal North Carolina, South Carolina and Georgia. Stroke belt includes the remaining parts of North Carolina, South Carolina and Georgia, and Tennessee, Mississippi, Alabama, Louisiana and Arkansas. Other US regions includes the remaining 40 contiguous US states and the District of Columbia
  4. b Rural area was defined based on census tract data
  5. Definitions for frailty indicators are provided in Supplemental Table 1. Definitions for other participant characteristics presented in this Table are provided in Supplemental Table 4