Table 5 Adjusted estimates of the association of prevalence of T2DM status at 5-year follow-up with change in cognitive performance between first and second cognitive assessment (5-year follow up of ESTHER cohort in 2005–2007 and 8-year follow-up in 2008–2010, N = 732) using the reliable change index
Generalized linear models, adjusted estimatesa for COGTEL scores | |||
|---|---|---|---|
Model 1 β (95%CI) | Model 2 β (95%CI) | Model 3 β (95%CI) | |
Working memory | -0.23 (-0.42 to -0.05) | -0.23 (-0.41 to -0.05) | -0.25 (-0.44 to -0.06) |
Inductive reasoning | -0.004 (-0.19 to 0.18) | -0.007 (-0.19 to 0.18) | -0.03 (-0.22 to 0.16) |
Verbal short-term memory | -0.11 (-0.29 to 0.08) | -0.11 (-0.29 to 0.08) | -0.14 (-0.33 to 0.04) |
Verbal long-term memory | -0.06 (-0.24 to 0.13) | -0.05 (-0.24 to 0.13) | -0.09 (-0.28 to 0.09) |
Verbal fluency | -0.08 (-0.27 to 0.10) | -0.09 (-0.27 to 0.10) | -0.10 (-0.28 to 0.09) |
Global cognitive function (COGTEL score) | -0.11 (-0.29 to 0.07) | -0.11 (-0.29 to 0.07) | -0.15 (-0.33 to 0.04) |
Age equivalent of difference in global cognitive function (years) | 3.4 | 3.4 | 4.4 |