Table 3 Adjusted estimates of the association of prevalence of T2DM with cognitive performance at first cognitive assessment (5-year follow up of ESTHER cohort, 2005–2007, N = 732)
Regression analysis, adjusted estimatesa for COGTEL sub-components and total score | |||
|---|---|---|---|
Model 1 | Model 2 | Model 3 | |
Prospective Memoryb, OR (95% CI) | 0.87 (0.72 to 1.06) | 0.87 (0.72 to 1.06) | 0.88 (0.72 to 1.08) |
Working memoryc, β (95% CI) | 0.34 (-0.13 to 0.81) | 0.33 (-0.14 to 0.81) | 0.46 (-0.02 to 0.95) |
Inductive reasoningc, β (95% CI) | -0.27 (-0.61 to 0.06) | -0.27 (-0.61 to 0.06) | -0.17 (-0.52 to 0.18) |
Verbal short-term memoryc, β (95% CI) | -0.36 (-0.71 to -0.01) | -0.36 (-0.71 to -0.01) | -0.29 (-0.65 to 0.07) |
Verbal long-term memoryc, β (95% CI) | -0.34 (-0.67 to -0.02) | -0.35 (-0.67 to -0.02) | -0.27 (-0.61 to 0.06) |
Verbal fluencyc, β (95% CI) | -0.86 (-1.97 to 0.25) | -0.86 (-1.97 to 0.25) | -0.29 (-1.43 to 0.85) |
Global cognitive function (COGTEL score)c, β (95% CI) | -1.48 (-3.06 to 0.09) | -1.49 (-3.07 to 0.08) | -0.91 (-2.53 to 0.72) |
Age equivalent of difference in global cognitive function (years) | 6.1 | 6.1 | 3.8 |