Table 2 Means and age- and sex-adjusted mean differences of cognitive performance* according to prevalence of T2DM at first and second cognitive assessment (5-year follow up of ESTHER cohort in 2005–2007 and 8-year follow-up in 2008–2010)
First cognitive measurement (N = 732) | Second cognitive measurement (N = 732) | |||||||
|---|---|---|---|---|---|---|---|---|
T2DM | T2DM-free | Ba | P-value | T2DM | T2DM-free | Ba | P-value | |
N | 143 | 589 | 185 | 547 | ||||
Prospective memory, N (%) | ||||||||
0 | 58 (40.6) | 190 (32.3) | 72 (38.9) | 176 (32.2) | ||||
1 | 85 (59.4) | 399 (67.7) | -0.16 | 0.092 | 113 (61.1) | 371 (67.8) | -0.14 | 0.108 |
Working memory, Mean (SD) | 6.6 (2.6) | 6.4 (2.5) | 0.28 | 0.237 | 7.4 (3.0) | 7.6 (2.5) | -0.13 | 0.575 |
Inductive reasoning, Mean (SD) | 3.2 (1.8) | 3.6 (1.8) | -0.36 | 0.044 | 3.2 (1.6) | 3.4 (1.8) | -0.16 | 0.298 |
Verbal short-term memory, Mean (SD) | 3.9 (1.7) | 4.3 (1.9) | -0.41 | 0.024 | 4.7 (1.8) | 5.1 (1.9) | -0.30 | 0.070 |
Verbal long-term memory, Mean (SD) | 4.4 (1.6) | 4.8 (1.7) | -0.39 | 0.023 | 5.4 (1.7) | 5.7 (1.7) | -0.17 | 0.236 |
Verbal fluency, Mean (SD) | 22.0 (6.0) | 23.3 (6.0) | -1.14 | 0.053 | 21.4 (5.9) | 22.8 (6.3) | -1.28 | 0.022 |
Global cognitive function (COGTEL score), Mean (SD) | 27.4 (8.3) | 29.4 (8.7) | -1.91 | 0.025 | 30.4 (8.3) | 31.9 (8.1) | -1.34 | 0.062 |