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Table 4 Association between inflammatory markers and low cognitive performance in the high and low MedDiet adherence groups

From: MedDiet adherence score for the association between inflammatory markers and cognitive performance in the elderly: a study of the NHANES 2011–2014

Variables

Model 1

Model 2

Model 3

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

Low MedDiet adherence groupa

 WBC count

1.47 (1.11–1.95)

0.005

1.46 (1.11–1.92)

0.005

1.44 (1.09–1.90)

0.008

 Lymphocyte count

1.37 (0.90–2.11)

0.132

1.48 (0.97–2.27)

0.059

1.45 (0.92–2.29)

0.093

 Neutrophil count

1.32 (1.04–1.67)

0.016

1.30 (1.03–1.64)

0.020

1.30 (1.03–1.65)

0.023

 NLR

1.21 (0.99–1.48)

0.050

1.17 (0.97–1.43)

0.096

1.16 (0.93–1.43)

0.166

 PLR

0.92 (0.75–1.13)

0.382

0.92 (0.75–1.13)

0.402

0.91 (0.73–1.13)

0.372

 NAR

1.36 (1.08–1.73)

0.007

1.35 (1.07–1.69)

0.008

1.34 (1.06–1.70)

0.012

High MedDiet adherence group

 WBC count

1.15 (0.98–1.35)

0.087

1.13 (0.96–1.32)

0.119

1.08 (0.93–1.25)

0.292

 Lymphocyte count

1.08 (0.82–1.44)

0.568

1.17 (0.74–1.85)

0.485

1.17 (0.74–1.86)

0.485

 Neutrophil count

1.12 (1.00–1.26)

0.044

1.09 (0.97–1.22)

0.132

1.05 (0.93–1.19)

0.411

 NLR

1.05 (0.97–1.14)

0.215

0.97 (0.91–1.10)

0.940

0.97 (0.88–1.07)

0.533

 PLR

0.87 (0.75–1.01)

0.051

0.86 (0.74–1.00)

0.042

0.86 (0.74–1.00)

0.036

 NAR

1.16 (1.03–1.30)

0.009

1.13 (1.01–1.27)

0.033

1.08 (0.97–1.22)

0.159

  1. MedDiet Mediterranean diet, WBC White blood cell, NLR Neutrophil–lymphocyte ratio, PLR Platelet-lymphocyte ratio, NAR Neutrophil-albumin ratio, OR Odds ratio, CI Confidence interval
  2. aIndividuals with the adherence score < 4 were classified into the low MedDiet adherence group, and individuals with the MedDiet adherence score ≥ 4 were classified into the high MedDiet adherence group
  3. Model 1, not adjusted for covariates
  4. Model 2, adjusted for age and gender
  5. Model 3, adjusted for age, gender, BMI, race/Hispanic origin, marital status, education, annual family income, sleep disorders, alcohol intake, recreational activities, depression, hypertension, diabetes, stroke, and heart failure