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Table 2 Associations of PWR and PNR with the risk of fatal stroke occurrence in the GBCS (n = 27,796)

From: Association of platelet-to-white blood cell ratio and platelet-to-neutrophil ratio with the risk of fatal stroke occurrence in middle-aged to older Chinese

 

Quartiles of PWR

Quartiles of PNR

 

the 1st (≤ 30)

the 2nd (30.01–36.11)

the 3rd (36.12–43.38)

the 4th (≥ 43.39)

the 1st (≤ 48.64)

the 2nd (48.65–61.11)

the 3rd (61.12–76.25)

the 4th (≥76.25)

All stroke

 Model 1 (HR, 95% CI)

1.00

0.71 (0.60–0.85), P < 0.001

0.61 (0.51–0.74), P < 0.001

0.46 (0.38–0.56), P < 0.001

1.00

0.64 (0.54–0.76), P < 0.001

0.56 (0.47–0.67), P < 0.001

0.38 (0.31–0.47), P < 0.001

 Model 2 (HR, 95% CI)

1.00

0.89 (0.74–1.06), P = 0.19

0.89 (0.74–1.07), P = 0.22

0.85 (0.69–1.05), P = 0.14

1.00

0.82 (0.68–0.97), P = 0.02

0.84 (0.70–1.01), P = 0.06

0.76 (0.61–0.94), P = 0.01

P for trend

0.38

0.03

Ischaemic stroke

 Model 1 (HR, 95% CI)

1.00

0.77 (0.61–1.00), P = 0.04

0.58 (0.44–0.75), P < 0.001

0.42 (0.31–0.56), P < 0.001

1.00

0.59 (0.46–0.75), P < 0.001

0.47 (0.36–0.61), P < 0.001

0.34 (0.26–0.47), P < 0.001

 Model 2 (HR, 95% CI)

1.00

0.99 (0.77–1.26), P = 0.93

0.88 (0.67–1.15), P = 0.35

0.84 (0.62–1.14), P = 0.26

1.00

0.77 (0.60–0.98), P = 0.04

0.74 (0.57–0.97), P = 0.03

0.74 (0.55–1.01), P = 0.05

P for trend

0.60

0.06

Haemorrhagic stroke

 Model 1 (HR, 95% CI)

1.00

0.57 (0.41–0.79), P = 0.001

0.60 (0.44–0.82), P = 0.002

0.43 (0.30–0.62), P < 0.001

1.00

0.62 (0.45–0.86), P = 0.004

0.65 (0.47–0.89), P = 0.007

0.40 (0.28–0.58), P < 0.001

 Model 2 (HR, 95% CI)

1.00

0.69 (0.50–0.95), P = 0.02

0.80 (0.58–1.11), P = 0.18

0.72 (0.49–1.03), P = 0.07

1.00

0.76 (0.55–1.05), P = 0.09

0.91 (0.66–1.26), P = 0.57

0.71 (0.48–1.04), P = 0.08

P for trend

0.10

0.21

Unclassified stroke

 Model 1 (HR, 95% CI)

1.00

0.80 (0.53–1.21), P = 0.29

0.73 (0.48–1.11), P = 0.14

0.61 (0.39–0.96), P = 0.03

1.00

0.83 (0.56–0.1.23), P = 0.34

0.65 (0.43–0.99), P = 0.04

0.44 (0.27–0.71), P = 0.001

 Model 2 (HR, 95% CI)

1.00

1.01 (0.67–1.53), P = 0.97

1.07 (0.70–1.64), P = 0.76

1.17 (0.74–1.86), P = 0.50

1.00

1.05 (0.71–1.57), P = 0.80

0.99 (0.65–1.53), P = 0.98

0.89 (0.55–1.47), P = 0.67

P for trend

0.91

0.94

  1. PWR platelet to white blood cell ratio, PNR platelet to neutrophil ratio, model 1 a crude hazard ratio model without adjustment for confounders, model 2 a multivariate model adjusted for age, sex, diabetes, hypertension, dyslipidaemia, smoking, alcohol consumption, physical activity, body mass index, self-rated health, cancer, genitourinary disease (nephropathy, prostatic disease, gynecologic diseases) and chest disease (COPD, chronic bronchitis, emphysema, asthma, tuberculosis, and pneumonia), and platelet count
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BMC Geriatrics

ISSN: 1471-2318

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