Associations of geriatric nutrition risk index and other nutritional risk-related indexes with sarcopenia presence and their value in sarcopenia diagnosis

Table 4 Diagnostic value of the concerned indexes for distinguishing between sarcopenia and non-sarcopenia

	AUC (95% CI)	Cut-off	Sensitivity (95% CI)	Specificity (95% CI)	Accuracy (95% CI)
In the entire study population (N = 3829)
GNRI	0.80 (0.78–0.82)	108.1	0.67 (0.63–0.71)	0.79 (0.78–0.81)	0.78 (0.76–0.79)
ALB	0.62 (0.60–0.65)	43.2 g/L	0.53 (0.48–0.57)	0.67 (0.66–0.69)	0.65 (0.64–0.67)
CC	0.83 (0.81–0.85)	34.0 cm	0.83 (0.80–0.87)	0.69 (0.67–0.7)	0.71 (0.69–0.72)
MAC	0.85 (0.83–0.86)	27.5 cm	0.80 (0.77–0.84)	0.74 (0.73–0.76)	0.75 (0.74–0.76)
TST	0.72 (0.70–0.74)	21.4 cm	0.65 (0.61–0.69)	0.68 (0.66–0.69)	0.67 (0.66–0.69)
BMI	0.81 (0.79–0.83)	23.4 kg/m²	0.75 (0.71–0.78)	0.74 (0.73–0.76)	0.74 (0.73–0.76)
In possible sarcopenia (N = 2436)
GNRI	0.80 (0.78–0.83)	108.1	0.67 (0.63–0.71)	0.79 (0.77–0.81)	0.77 (0.75–0.78)
ALB	0.60 (0.57–0.62)	42.0 g/L	0.39 (0.35–0.43)	0.78 (0.76–0.80)	0.70 (0.68–0.72)
CC	0.82 (0.80–0.84)	34.0 cm	0.83 (0.80–0.87)	0.68 (0.66–0.70)	0.71 (0.69–0.73)
MAC	0.85 (0.83–0.87)	27.5 cm	0.80 (0.77–0.84)	0.74 (0.72–0.76)	0.76 (0.74–0.77)
TST	0.73 (0.71–0.75)	21.4 cm	0.65 (0.61–0.69)	0.69 (0.67–0.71)	0.68 (0.66–0.70)
BMI	0.83 (0.81–0.85)	23.4 kg/m²	0.75 (0.71–0.78)	0.77 (0.75–0.79)	0.76 (0.75–0.78)

Note: The AUCs of all the concerned indexes were significantly larger than the area under the diagnostic reference line (P<0.05). Sensitivity, specificity and accuracy all referred to the corresponding diagnostic measures at the optimal cut-off values
Abbreviations: AUC area under the receiver operating characteristic curve, CI confidence interval, Cut-off the optimal cut-off value determined according to Youden’s index, GNRI geriatric nutrition risk index, ALB albumin, CC calf circumference, MAC mid-arm circumference, TST triceps skinfold thickness, BMI body mass index

ISSN: 1471-2318