Table 3 Intention to treat analyses of the between and within group changes from baseline to three months
Group (Number of residents with symptoms) | Baseline INT n = 159 CTR n = 150 | 3 months INT n = 135 CTRL n = 136 | Between groups at 3 months | Within groups (3 months–baseline) | ICC | |||
|---|---|---|---|---|---|---|---|---|
Mean ± SD | Mean ± SD | Est. diff. (95% CI) | p-value | Change (95%CI) | p-value | |||
Total NPI-Q | INT (129) | 4.5 ± 5.2 | 3.9 ± 3.7 | -1.0 (-2.4, 0.5) | 0.19 | -0.4 (-1.4, 0.6) | 0.42 | 0.07 |
(Range 0–36) | CTRL (121) | 4.9 ± 5.4 | 5.4 ± 6.0 | 0.5 (-0.5,1.6) | 0.30 | |||
Agitation | INT (76) | 1.4 ± 1.9 | 1.5 ± 2.0 | -0.2 (-0.8, 0.4) | 0.54 | 0.1 (-0.3,0.5) | 0.64 | 0.03 |
(Range 0–9) | CTRL (83) | 1.7 ± 2.1 | 2.0 ± 2.5 | 0.3 (-0.1,0.7) | 0.18 | |||
Affective | INT (60) | 0.7 ± 1.1 | 0.6 ± 1.0 | 0.05 (-0.2, 0.3) | 0.67 | -0.1 (-0,3, 0.1) | 0.40 | 0.00 |
(Range 0–6) | CTRL (62) | 1.0 ± 1.4 | 0.8 ± 1.4 | -0.1 (-0.3, 0.0) | 0.15 | |||
Psychosis | INT (68) | 0.8 ± 1.2 | 0.8 ± 1.2 | -0.25 (-0.5, 0.1) | 0.11 | -0.07 (-0.3,0.2) | 0.55 | 0.04 |
(Range 0–6) | CTRL (63) | 0.8 ± 1.2 | 0.9 ± 1.3 | 0.18 (-0.0,0.4) | 0.10 | |||
Apathy | INT (43) | 0.7 ± 1.1 | 0.5 ± 0.8 | -0.5 (-0.9, -0.05) * | 0.03 | -0.2 (-0.5,0.1) | 0.24 | 0.10 |
(Range 0–3) | CTRL (37) | 0.6 ± 1.1 | 0.9 ± 1.3 | 0.3 (-0.01,0.6) | 0.06 | |||