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Table 3 Intention to treat analyses of the between and within group changes from baseline to three months

From: The short-term effect of a modified comprehensive geriatric assessment and regularly case conferencing on neuropsychiatric symptoms in nursing homes: a cluster randomized trial

Group (Number of residents with symptoms) Baseline INT n = 159 CTR n = 150 3 months INT n = 135 CTRL n = 136 Between groups at 3 months Within groups (3 months–baseline) ICC
Mean ± SD Mean ± SD Est. diff. (95% CI) p-value Change (95%CI) p-value
Total NPI-Q INT (129) 4.5 ± 5.2 3.9 ± 3.7 -1.0 (-2.4, 0.5) 0.19 -0.4 (-1.4, 0.6) 0.42 0.07
(Range 0–36) CTRL (121) 4.9 ± 5.4 5.4 ± 6.0    0.5 (-0.5,1.6) 0.30  
Agitation INT (76) 1.4 ± 1.9 1.5 ± 2.0 -0.2 (-0.8, 0.4) 0.54 0.1 (-0.3,0.5) 0.64 0.03
(Range 0–9) CTRL (83) 1.7 ± 2.1 2.0 ± 2.5    0.3 (-0.1,0.7) 0.18  
Affective INT (60) 0.7 ± 1.1 0.6 ± 1.0 0.05 (-0.2, 0.3) 0.67 -0.1 (-0,3, 0.1) 0.40 0.00
(Range 0–6) CTRL (62) 1.0 ± 1.4 0.8 ± 1.4    -0.1 (-0.3, 0.0) 0.15  
Psychosis INT (68) 0.8 ± 1.2 0.8 ± 1.2 -0.25 (-0.5, 0.1) 0.11 -0.07 (-0.3,0.2) 0.55 0.04
(Range 0–6) CTRL (63) 0.8 ± 1.2 0.9 ± 1.3    0.18 (-0.0,0.4) 0.10  
Apathy INT (43) 0.7 ± 1.1 0.5 ± 0.8 -0.5 (-0.9, -0.05) * 0.03 -0.2 (-0.5,0.1) 0.24 0.10
(Range 0–3) CTRL (37) 0.6 ± 1.1 0.9 ± 1.3    0.3 (-0.01,0.6) 0.06  
  1. The between group estimated mean differences and the within-group group differences have been calculated using mixed linear model
  2. INT Intervention group, CTR Control group, CI Confidence Interval, NPI-Q, 12-items: Neuropsychiatric inventory, 12-items, ICC model based Intra Class Correlation on change score. Coefficient, SD standard Deviation
  3. *p-value ≤ 0.05