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Table 2 Medications recommended avoiding for people at risk of delirium [39,40,41,42]

From: Impact of a dementia-friendly program on detection and management of patients with cognitive impairment and delirium in acute-care hospital units: a controlled clinical trial design

Medications

Recommendation

Tricyclic antidepressants

Should be avoided

Antipsychotic medications

High-dose antipsychotic medications should be avoided; if necessary, haloperidol, risperidone or quetiapine can be used

Histamine antagonists

Hydroxyzine and alimemazine are not recommended

Corticosteroids

Use caution with high-dose corticosteroids

Anticholinergic and beta-3 adrenergic agonist

Oksybutynin/tolterodine/solifenacin/

Darifenacin/fesoterodine/Mirabegron are not recommended

Benzodiazepines

Should be avoided, but do not quit abruptly after prolonged use

Opioid analgesics

Not recommended, but can/must sometimes be used

Metoclopramide

Not recommended but can/must sometimes be used

Clomethiazole

Could be used to induce sleep at night

Others

Caution with Digoxin and Lithium; monitor S-concentration