Dependent variable | Unadjusted models a | Adjusted models b |
|---|
β | B | 95% CI for B | β | B | 95% CI for B |
|---|
Grip strength (kg) | 0.05 | 0.01 | −0.02 to 0.03 | 0.03 | 0.01 | −0.02 to 0.03 |
SPPB (0-12) | 0.26 | 0.02 | 0.00 to 0.03 | 0.19 | 0.01 | 0.00 to 0.02 |
Gait speed (m/s) | 0.24 | 0.001 | 0.000 to 0.002 | 0.23 | 0.001 | 0.000 to 0.002 |
- β is the standardized regression coefficient. B is the unstandardized regression coefficient and equals the estimated change in the dependent variable per milligram increase in statin exposure expressed as simvastatin equivalents, taking into account statin potency, drug-drug interactions and SLCO1B1 genotype. Estimates in bold letters indicate a p-value below 0.05
- aModel for grip strength adjusted for gender
- bAll models adjusted for age, gender, body mass index, Cumulative Illness Rating Scale, Functional Independence Measure and Clinical Dementia Rating Scale
