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Table 4 Postoperative outcomes of patients with POD

From: Postoperative cognitive dysfunction in older surgical patients associated with increased healthcare utilization: a prospective study from an upper-middle-income country

Variable

No POD

(n = 247)

POD

(n = 26)

P value

Barthel ADL Index at 3 months

93.69 ± 12.68

87.63 ± 19.95

0.06

Declined basic ADL n (%); score reduced ≥ 5 points

49 (25.1%)

6 (31.6%)

0.58

Declined IADL score 2, n (%); score reduced ≥ 2 points

44 (22.7%)

9 (47.4%)

0.03*

IADL score at 3 months

6.33 ± 1.89

5.10 ± 2.42

0.04*

Worsened quality of life at 3 months, n (%)

57 (28.9%)

7 (36.8%)

0.60

Health utility, score

0.90 ± 0.15

0.86 ± 0.19

0.33

Frailty at 3 months, (3–5), n (%)

22 (11.3%)

3 (15.8%)

0.47

Readmission at 3 months, n (%)

32 (13.2%)

6 (25.0%)

0.13

Mortality at 3 months, n (%)

6 (2.4%)

7 (26.9%)

 < 0.001*

Hospital LOS, days; median (min, max)

8 (1, 57)

17 (5, 70)

 < 0.001*

Total cost, USD; median (min, max)

5981.68 (332.04, 53 455.42)

11 501.52 (2857.64, 86 953.34)

 < 0.001*

ICU LOS, days; median (min, max)

1 (0, 57)

5 (0, 53)

 < 0.001*

Ventilator, days; median (min, max);

1 (0, 11)

1 (0, 57)

 < 0.001*

  1. * Indicates statistical significance (< 0.05)
  2. POD includes participants who had DSM-5 administered to establish their POD status but did not include patients with POCD
  3. Abbreviations:ADL activities of daily living, FRAIL Fatigue, Resistance, Ambulation, Illnesses, and Loss of weight, IADL Lawton–Brody instrumental activities of daily living, ICU intensive care unit, LOS length of stay, POD postoperative delirium; ventilator, length of time on a ventilator