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Table 1 Baseline characteristics of the population (n = 530)

From: Association between orthostatic blood pressure dysregulation and geriatric syndromes: a cross-sectional study

Male sex

179 (33)

Age (years)

82.9 ± 5.2

Comorbidities

  Hypertension

387 (73)

  Diabetes mellitus

132 (24.9)

  Heart failure

80 (15.1)

  Vascular disease

86 (16.2)

    -Stroke

32 (6)

    -Peripheral arterial disease

54 (10.2)

    -Coronary heart disease

22 (4.2)

    -Carotid stenosis

62 (11.7)

  Atrial fibrillation

111 (20.9)

  Chronic kidney disease

151 (28.5)

  eGFR CKD-EPI (mL/min)

65.6 ± 20.3

Resting hemodynamic parameters

  SBP (mmHg)

145 ± 25.2

  DBP (mmHg)

72.7 ± 11.5

  PP (mmHg)

72.3 ± 19.9

  MBP (mmHg)

96.8 ± 14.5

  HR (bpm)

70.5 ± 11.8

Antihypertensive medications

  Treatment for hypertension

401 (75.7)

  Number of antihypertensive drugs

 

  -1

153 (28.9)

  -2

132 (24.9)

  -3 or more

113 (21.3)

  Type of antihypertensive medications

 

  -ACEi/ARB

223 (42)

  -CCB

137 (25.8)

  -ß-blockers

183 (34.6)

  -Diuretics

168 (31.7)

  -Centrally-acting antihypertensive agents

36 (6.8)

  -⍺-blockers

44 (8.3)

Geriatric characteristics

  IADL

3.0 ± 2.6

  BADL

5.0 ± 1.0

  BADL ≤ 5

257 (48.6)

  Depression

186 (35.5)

  Mini-GDS ≥ 1

111 (40.3)

  Dementia

362 (68.3)

  MMSe score, /30

19.2 ± 5.8

  Pathological MMSa

362 (72.5)

  MMSe severity

 

  -mild

113 (31.2)

  -moderate

195 (53.8)

  -severe

54 (14.9)

  Pathological CDT

248 (58.3)

   ≥ 1 self-reported fall in the last 6 months

213 (40.3)

  Malnutritionb

97 (18)

  BMI (kg/m2)

27.1 ± 4.8

  Albumin (g/L)

39.8 ± 4.3

  Sarcopeniac

305 (57)

  Hand-grip strength (kg)

16.7 ± 7.5

  Low hand-grip strengthd

402 (75.8)

  Walking speed (m/s)

0.67 ± 0.25

  Low walking speede

365 (69.7)

  1. Results are expressed as mean ± SD or n (%). eGFR CKD-EPI estimated Glomerular Filtration Rate by CKD-EPI Formula; SBP Systolic Blood Pressure, DBP Diastolic Blood Pressure, PP Pulse Pressure, MBP Mean Blood Pressure, HR Heart rate, ACEi/ARB Angiotensin-Converting Enzyme inhibitors/Angiotensin II Receptor Blockers, CCB Calcium-Channel Blockers, BMI Body Mass Index, BADL Basic Activities of Daily Living, IADL Instrumental Activities of Daily Living, Mini-GDS 4-items Geriatric Depression Scale, MMSe Mini-Mental State Examination, CDT French GRECO version of the Clock Drawing Test
  2. aMMSe was considered pathological when lower than threshold defined according to age and socio-educative level; bMalnutrition was defined as BMI lower than 21 kg/m2 or albuminemia lower than 35 g/L; cSarcopenia was defined as low walking speed and low hand-grip strength; dLow hand-grip strength was defined according to threshold depending on sex and BMI; eWalking speed < 0.8 m/sec was considered low