Sarcopenia and motoric cognitive risk syndrome: a moderated mediation model

BMC Geriatrics

Table 4 Path analysis of the mediation and moderated mediation model using structural equation modelling

Dependent variable	Independent variable	Effect	Estimate	SE	Est/SE	P value	BootLLCI	BootLLCI
Mediation model
Apathy	Sarcopenia		3.241	0.896	3.615	< 0.001	1.467	4.954
MCR	Sarcopenia		1.456	0.476	3.061	0.002	0.442	2.282
	Apathy		0.097	0.025	3.813	< 0.001	0.043	0.140
		Direct effect	1.456	0.476	3.061	0.002	0.442	2.282
		Direct effect odds ratio	4.289	2.770	1.549	0.121	1.556	9.799
		Indirect effect	0.314	0.117	2.685	0.007	0.116	0.559
		Indirect effect odds ratio	1.369	0.170	8.031	< 0.001	1.123	1.750
Moderated mediation model
Apathy	Sarcopenia		2.097	0.926	2.265	0.024	0.329	3.908
	Physical activity		-1.234	0.276	-4.467	< 0.001	-1.766	-0.673
	Sarcopenia*Physical activity		-1.958	0.791	-2.475	0.013	-3.438	-0.272
MCR	Sarcopenia		1.456	0.476	3.061	0.002	0.442	2.282
	Apathy		0.097	0.025	3.813	< 0.001	0.043	0.140

MCR motoric cognitive risk syndrome, SE standard error, Est/SE estimate divided by the standard error. BootLLCI / BootLLCI, lower/upper 2.5% of bias-corrected confidence interval derived from bootstrap estimates. Adjusted for gender, body mass index, and all potential confounding factors

ISSN: 1471-2318