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Table 4 Effects of prenatal and childhood variables on physical capability tests adjusted by adulthood variables

From: Physical capability in a rural birth cohort at the age of 52: association with early environmental, nutritional, and developmental factors

 

Variable

Coefficient (95% CI)

P

Adulthood variables included in the model

AdjustedR2

N

Grip strength (kg)

Z score of weight for age at birth (S.D.)

4.5 (0.6 to 8.4)

0.027

Phase angle, Depression score

0.4633

29

Z score of head circumference at birth (S.D.)

2.14 (0.77 to 3.51)

0.012

Sex, energy expenditure, pulse pressure, depression score

0.9916

10

Prenatal family SES (The higher the value, the lower the status)

-0.44 (-0.75 to -0.14)

0.005

Sex, lean mass index, pulse pressure

0.7894

72

Post-gestational maternal BMI (kg/m2)

0.27 (0.01 to 0.53)

0.040

Sex, adult height, energy expenditure, phase angle, depression score

0.8688

79

Prenatal paternal BMI at birth (kg/m2)

0.31 (0.01 to 0.62)

0.040

Sex, adult height, lean mass index, pulse pressure, energy expenditure

0.8673

75

Number of family members at birth

0.67 (0.34 to 0.99)

 < 0.001

Sex, adult height, lean mass index, pulse pressure, energy expenditure

0.8899

78

Increase in arm circumference from 3rd to 4th month (cm)

-1.17 (-2.24 to -0.1)

0.033

Sex, height, lean mass index, depression score, pulse pressure, energy expenditure

0.8749

74

Z score of weight increase from birth to 6 months

-1 Z to <  + 1 Z (vs < -1 Z)

-1.67 (-3.49 to 1.49)

0.071

Sex, height, lean mass index, energy expenditure, phase angle, pulse pressure, depression score

0.8867

74

 >  + 1 Z (vs < -1 Z)

-2.78 (-5.39 to -1.75)

0.037

Z score of head circumference increase from birth to 6 months

 < -2 Z (vs -2 Z to + 1 Z)

-0.58 (-2.92 to 1.77)

0.625

Sex, height, lean mass index, energy expenditure, angle phase, pulse pressure, depression score

0.893

74

 >  + 1Z (vs -2 Z to + 1 Z)

-3.19 (-5.27 to -1.11)

0.003

Gait speed (cm/s)

Living in a nuclear (vs extended) family at birth

-11.06 (-21.75 to -0.37)

0.0427

Right leg length, foot width, BMI, diabetes mellitus, MMSE result, blood uric acid

0.2906

80

Weaning age (months)

0.55 (0.02 to 1.07)

0.0423

Sex, right leg length, knee height, BMI, grip strength, blood uric acid, resting diastolic blood pressure, resting respiratory rate

0.4958

61

Prenatal father's education level (years)

1.5 (0.43 to 2.57)

0.0067

Sex, right leg length, foot width, BMI, grip strength, resting diastolic blood pressure, blood uric acid, diabetes mellitus, MMSE

0.4902

76

Post-gestational Mother's BMI

 < 19 kg/m2 (vs normal)

-32.86 (-62.43 to -3.28)

0.0300

Right leg length, knee height, grip strength, BMI, diabetes mellitus, blood uric acid

0.3968

79

 ≥ 25 kg/m2 (vs normal)

-8.64 (-15.84 to -1.44)

0.0193

Prenatal family's socioeconomic status

Medium (vs High)

-3.09 (-11.76 to 5.58)

0.4786

Sex, right leg length, knee height, foot width, grip strength, BMI, resting diastolic blood pressure, resting respiratory rate

0.4331

72

Low (vs High)

-11.83 (-21.97 to -1.68)

0.0231

Prenatal Mother's Height Z score

 < -1.5 Z score (vs ≥ -1.5 to < 0 Z)

-13.78 (-22.87 to -4.69)

0.0035

Right leg length, grip strength, BMI, diabetes mellitus

0.3415

79

 ≥ 0 Z score (vs ≥ -1.5 to < 0 Z)

-32.07 (-64.04 to -0.1)

0.0493

Head circumference growth velocity from 0 to 6 months age (Z score)

 < -2 Z score (vs -2 to <  + 1 Z)

-16.75 (-27.32 to -6.18)

0.0023

Right leg length, foot width, BMI, resting diastolic blood pressure, resting respiratory rate

0.3252

75

 ≥  + 1 Z score (vs -2 to <  + 1 Z)

-13.5 (-22.96 to -4.05)

0.0058

Chair stand test (stands/30 s)

Weaning age (months)

-0.12 (-0.21 to -0.03)

0.0110

Sex, adult height, frailty index

0.2721

61

  1. *Every childhood variable coefficient corresponds to a single and different multivariable model