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Table 4 Crude and multivariable Cox proportional hazards regression, presenting the crude Hazard Ratio (HR) and adjusted HR (aHR) for the time to discharge

From: Prognostic value of estimated glomerular filtration rate in hospitalised older patients (over 65) with COVID-19: a multicentre, European, observational cohort study

 

Crude

Multivariable

HR (95%CI)

p

aHR

p

eGFR (60+)

 1–29

0.79 (0.61–1.03)

0.0796

0.84 (0.64–1.09)

0.1833

 30–44

0.97 (0.79–1.20)

0.8071

1.09 (0.88–1.35)

0.4255

 45–59

0.99 (0.82–1.20)

0.9433

1.09 (0.89–1.32)

0.4121

Wave 2

0.61 (0.51–0.73)

< 0.001

0.60 (0.50–0.73)

< 0.001

Age (65–74)

 75–84

0.85 (0.72–0.99)

0.0417

0.89 (0.75–1.06)

0.1830

 85–94

0.70 (0.58–0.85)

< 0.001

0.72 (0.58–0.89)

0.0022

 95+

0.64 (0.33–1.25)

0.1935

0.77 (0.39–1.51)

0.4405

Male

0.97 (0.84–1.12)

0.7133

0.93 (0.80–1.08)

0.3394

Smoking (Never)

 Ex-smoker

1.07 (0.93–1.24)

0.3373

1.10 (0.94–1.28)

0.2235

 Current smoker

0.98 (0.71–1.35)

0.9104

0.97 (0.70–1.35)

0.8677

CRP > 40

1.15 (0.99–1.33)

0.0712

1.07 (0.92–1.24)

0.4077

Diabetes

0.91 (0.78–1.06)

0.2364

0.92 (0.78–1.09)

0.3529

CAD

0.96 (0.82–1.13)

0.6435

1.01 (0.85–1.20)

0.9002

Hypertension (No)

 Yes

0.87 (0.71–1.08)

0.2059

0.97 (0.78–1.20)

0.7580

 Yes & on treatment

1.09 (0.93–1.28)

0.2812

1.08 (0.92–1.28)

0.3466

CFS (1–3)

 CFS 4

0.83 (0.66–1.03)

0.0960

0.89 (0.71–1.12)

0.3103

 CFS 5–6

0.71 (0.59–0.85)

< 0.001

0.78 (0.64–0.95)

0.0157

 CFS 7–8

0.71 (0.57–0.87)

0.0014

0.79 (0.63–0.99)

0.0380

  1. Note: aHR adjusted for eGFR, wave, age, sex, smoking status, CRP, diabetes, CAD, hypertension and CFS