Table 2 Crude and multivariable Cox proportional hazards regression, presenting the crude Hazard Ratio (HR) and adjusted HR (aHR) for the time to mortality

 1–29

1.55 (1.24–1.95)

< 0.001

1.42 (1.13–1.80)

0.0031

 30–44

1.54 (1.26–1.89)

< 0.001

1.41 (1.14–1.73)

0.0014

 45–59

1.30 (1.06–1.60)

0.0125

1.26 (1.02–1.55)

0.0295

Wave 2

0.75 (0.62–0.91)

0.0036

0.77 (0.63–0.94)

0.0093

 75–84

1.52 (1.25–1.85)

< 0.001

1.44 (1.17–1.77)

< 0.001

 85–94

1.78 (1.44–2.21)

< 0.001

1.60 (1.27–2.01)

< 0.001

 95+

2.74 (1.78–4.22)

< 0.001

2.61 (1.67–4.09)

< 0.001

Male

1.13 (0.97–1.32)

0.1203

1.20 (1.02–1.41)

0.0279

 Ex-smoker

1.22 (1.05–1.42)

0.0112

1.14 (0.97–1.33)

0.1204

 Current smoker

0.96 (0.67–1.38)

0.8157

0.94 (0.65–1.37)

0.7450

CRP > 40

1.81 (1.52–2.16)

< 0.001

1.81 (1.51–2.16)

< 0.001

Diabetes

1.03 (0.88–1.22)

0.6902

0.99 (0.83–1.17)

0.8650

CAD

1.17 (0.99–1.38)

0.0722

1.03 (0.87–1.23)

0.7170

 Yes

0.90 (0.72–1.12)

0.3506

0.91 (0.72–1.14)

0.4008

 Yes & on treatment

0.86 (0.72–1.01)

0.0682

0.85 (0.71–1.01)

0.0653

 CFS 4

1.39 (1.06–1.81)

0.0158

1.28 (0.97–1.67)

0.0791

 CFS 5–6

1.48 (1.18–1.86)

< 0.001

1.30 (1.02–1.66)

0.0327

 CFS 7–8

1.91 (1.50–2.43)

< 0.001

1.63 (1.26–2.11)

< 0.001