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Table 2 Laboratory results according to clinical outcomes

From: Chronic diseases, chest computed tomography, and laboratory tests as predictors of severe respiratory failure and death in elderly Brazilian patients hospitalized with COVID-19: a prospective cohort study

Variables

(n. %)

Total

(n = 201)

Mechanical Ventilation (n = 34)

No MV

(n = 167)

p

Death

(n = 16)

No death

(n = 185)

p

Laboratory tests abnormalities (in quartiles)

 Higher CRP (mg/L)

51 (25.4)

19 (55.9)

32 (19.2)

< 0.001

9 (56.3)

42 (22.7)

0.006

 Higher IL-6 (pg/mL)

49 (24.4)

15 (44.1)

34 (20.4)

0.004

9 (56.3)

40 (21.6)

0.004

 Higher d-Dimer (ng/mL)

51 (25.4)

18 (52.9)

33 (19.8)

< 0.001

10 (62.5)

41 (22.2)

0.001

 Higher ALT (U/mL)

51 (25.4)

9 (26.5)

42 (25.1)

0.512

3 (18.8)

48 (25.9)

0.384

Higher AST (U/mL)

51 (25.4)

16 (47.1)

35 (21.0)

0.002

6 (37.5)

45 (24.3)

0.191

 Lower Hemoglobin (g/mL)

51 (25.4)

18 (52.9)

33 (19.8)

< 0.001

10 (62.5)

41 (22.2)

0.001

 Higher Leucocytes (/μL)

49 (24.4)

12 (35.3)

37 (22.2)

0.082

7 (43.8)

42 (22.7)

0.063

 Higher Creatinine (mg/dL)

50 (24.9)

14 (41.2)

36 (21.6)

0.017

9 (56.3)

41 (22.2)

0.005

 Higher Myoglobin (ng/mL)

50 (25.0)

19 (55.9)

31 (18.7)

< 0.001

9 (56.3)

41 (22.3)

0.005

 Lower Vitamin D (ng/dL)

48 (23.9)

45 (26.9)

3 (8.8)

0.026

2 (12.5)

46 (24.9)

0.215

 Lower Lymphocytes (/μL)

49 (24.4)

17 (50.0)

32 (19.2)

< 0.001

6 (37.5)

43 (23.2)

0.165

Laboratories variables (means ± SD)

 CRP (mg/L)

54.88 (58.92)

94.97 (68.87)

46.71 (53.32)

< 0.001

98.28 (67.97)

51.12 (56.73)

0.002

 IL-6 (pg/mL)

39.50 (60.58)

83.87 (99.40)

30.46 (44.41)

< 0.001

96.58 (85.19)

34.56 (55.59)

0.000

 D-Dimer (ng/mL)

886.16 (1002.79)

1426.05 (1432.77)

776.25 (855.34)

0.002

1382.06 (977.41)

843.28 (995.95)

0.039

 ALT (U/mL)

39.45 (33.84)

37.88 (27.89)

39.77 (34.99)

0.767

37.00 (33.70)

39.67 (33.94)

0.763

 AST (U/mL)

35.20 (23.53)

47.00 (30.85)

32.80 (21.06)

0.001

50.87 (39.25)

33.84 (21.29)

0.005

 Hemoglobin (g/mL)

12.77 (1.94)

11.73 (2.16)

12.98 (1.83)

0.001

11.23 (2.18)

12.90 (1.86)

0.001

 Leucocytes (/μL)

7012.95 (3410.39)

8552.08 (3246.08)

6699.60 (3366.65)

0.004

9013.12 (3116.15)

6839.97 (3387.12)

0.014

 Creatinine (mg/dL)

1.05 (0.63)

1.31 (0.865)

1.00 (0.56)

0.009

1.27 (0.48)

1.03 (0.64)

0.146

 Myoglobin (ng/mL)

68.25 (147.88)

163.19 (328.13)

48.81 (51.03)

< 0.001

135.82 (180.03)

62.38 (143.84)

0.057

 Vitamin D (ng/dL)

33.01 (15.47)

28.41 (9.98)

33.95 (16.22)

0.057

29.62 (9.89)

33.30 (15.84)

0.362

 Lymphocytes (/μL)

1019.56 (599.60)

697.61 (403.83)

1085.10 (612.52)

0.001

863.62 (427.83)

1033.04 (611.20)

0.279

  1. Legend: C-reactive protein (CRP), interleukin 6 (IL-6), alanine transaminase (ALT), aspartate aminotransferase (AST)
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