Variables (n. %) | Total (n = 201) | Mechanical Ventilation (n = 34) | No MV (n = 167) | p | Death (n = 16) | No death (n = 185) | p |
---|---|---|---|---|---|---|---|
Laboratory tests abnormalities (in quartiles) | |||||||
Higher CRP (mg/L) | 51 (25.4) | 19 (55.9) | 32 (19.2) | < 0.001 | 9 (56.3) | 42 (22.7) | 0.006 |
Higher IL-6 (pg/mL) | 49 (24.4) | 15 (44.1) | 34 (20.4) | 0.004 | 9 (56.3) | 40 (21.6) | 0.004 |
Higher d-Dimer (ng/mL) | 51 (25.4) | 18 (52.9) | 33 (19.8) | < 0.001 | 10 (62.5) | 41 (22.2) | 0.001 |
Higher ALT (U/mL) | 51 (25.4) | 9 (26.5) | 42 (25.1) | 0.512 | 3 (18.8) | 48 (25.9) | 0.384 |
Higher AST (U/mL) | 51 (25.4) | 16 (47.1) | 35 (21.0) | 0.002 | 6 (37.5) | 45 (24.3) | 0.191 |
Lower Hemoglobin (g/mL) | 51 (25.4) | 18 (52.9) | 33 (19.8) | < 0.001 | 10 (62.5) | 41 (22.2) | 0.001 |
Higher Leucocytes (/μL) | 49 (24.4) | 12 (35.3) | 37 (22.2) | 0.082 | 7 (43.8) | 42 (22.7) | 0.063 |
Higher Creatinine (mg/dL) | 50 (24.9) | 14 (41.2) | 36 (21.6) | 0.017 | 9 (56.3) | 41 (22.2) | 0.005 |
Higher Myoglobin (ng/mL) | 50 (25.0) | 19 (55.9) | 31 (18.7) | < 0.001 | 9 (56.3) | 41 (22.3) | 0.005 |
Lower Vitamin D (ng/dL) | 48 (23.9) | 45 (26.9) | 3 (8.8) | 0.026 | 2 (12.5) | 46 (24.9) | 0.215 |
Lower Lymphocytes (/μL) | 49 (24.4) | 17 (50.0) | 32 (19.2) | < 0.001 | 6 (37.5) | 43 (23.2) | 0.165 |
Laboratories variables (means ± SD) | |||||||
CRP (mg/L) | 54.88 (58.92) | 94.97 (68.87) | 46.71 (53.32) | < 0.001 | 98.28 (67.97) | 51.12 (56.73) | 0.002 |
IL-6 (pg/mL) | 39.50 (60.58) | 83.87 (99.40) | 30.46 (44.41) | < 0.001 | 96.58 (85.19) | 34.56 (55.59) | 0.000 |
D-Dimer (ng/mL) | 886.16 (1002.79) | 1426.05 (1432.77) | 776.25 (855.34) | 0.002 | 1382.06 (977.41) | 843.28 (995.95) | 0.039 |
ALT (U/mL) | 39.45 (33.84) | 37.88 (27.89) | 39.77 (34.99) | 0.767 | 37.00 (33.70) | 39.67 (33.94) | 0.763 |
AST (U/mL) | 35.20 (23.53) | 47.00 (30.85) | 32.80 (21.06) | 0.001 | 50.87 (39.25) | 33.84 (21.29) | 0.005 |
Hemoglobin (g/mL) | 12.77 (1.94) | 11.73 (2.16) | 12.98 (1.83) | 0.001 | 11.23 (2.18) | 12.90 (1.86) | 0.001 |
Leucocytes (/μL) | 7012.95 (3410.39) | 8552.08 (3246.08) | 6699.60 (3366.65) | 0.004 | 9013.12 (3116.15) | 6839.97 (3387.12) | 0.014 |
Creatinine (mg/dL) | 1.05 (0.63) | 1.31 (0.865) | 1.00 (0.56) | 0.009 | 1.27 (0.48) | 1.03 (0.64) | 0.146 |
Myoglobin (ng/mL) | 68.25 (147.88) | 163.19 (328.13) | 48.81 (51.03) | < 0.001 | 135.82 (180.03) | 62.38 (143.84) | 0.057 |
Vitamin D (ng/dL) | 33.01 (15.47) | 28.41 (9.98) | 33.95 (16.22) | 0.057 | 29.62 (9.89) | 33.30 (15.84) | 0.362 |
Lymphocytes (/μL) | 1019.56 (599.60) | 697.61 (403.83) | 1085.10 (612.52) | 0.001 | 863.62 (427.83) | 1033.04 (611.20) | 0.279 |