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Table 3 Cognitive abilities and neuropsychological tests used in assessment in included studiesa

From: Is there an association between non-alcoholic fatty liver disease and cognitive function? A systematic review

Cognitive abilities Neuropsychological testsb Cognitive impairment seen in NAFLD No difference seen in NAFLD Study
General Cognition Montreal Cognitive Assessment test Serbian version +   Filipovic et al. 2018 [21]
Montreal Cognitive Assessment Turkish version +   Celikbilek et al. 2018 [22]
Mini Mental State Examination +   Tuttolomondo et al. 2018 [33]
Cognitive Failures Questionnaire +   Elliott et al. 2013 [23]
Reasoning Raven’s Progressive Matrices   – Tarter et al. 1984 [30]
Mental speed, Attention and Psychomotor speed Digit Symbol Substitution Test +   Weinstein et al. 2018 [27]
MoCA-TR Attention: Sustained attention task   – Celikbilek et al. 2018 [22]
MoCA-TR Attention: A serial subtraction task   – Celikbilek et al. 2018 [22]
MoCA-TR Attention: Digits forward and backward tasks   – Celikbilek et al. 2018 [22]
Digit span forward   – Tarter et al. 1984 [30]
Digit span backward   – Tarter et al. 1984 [30]
Mental control   – Tarter et al. 1984 [30]
Purdue Pegboard +   Tarter et al. 1984 [30]
Stary Tracing   – Tarter et al. 1984 [30]
Symbol Digit Substitution Test +   Seo et al. 2016 [32]
The Simple Reaction Time Test +   Seo et al. 2016 [32]
Symbol Digit Modalities Test +   Tarter et al. 1984 [30]
The number connection test A   – Felipo et al. 2012 [24]
The number connection test B   – Felipo et al. 2012 [24]
  The Serial Dotting Test   – Felipo et al. 2012 [24]
Memory and learning The Wechsler Memory Scale (verbal and visual)   – Weinstein et al. 2019 [29]
Logical memory   – Tarter et al. 1984 [30]
Figural memory   – Tarter et al. 1984 [30]
Paired associates   – Tarter et al. 1984 [30]
Supraspan - Weschler Memory Scale   – Tarter et al. 1984 [30]
Supraspan Learning Test +   Tarter et al. 1987 [31]
Digit Span Test   – Tarter et al. 1987 [31]
Benton Visual Retention Test +   Tarter et al. 1987 [31]
Rey-Osterreith Complex Figure Test   – Tarter et al. 1987 [31]
Brown-Peterson Test   – Tarter et al. 1987 [31]
The Serial Digit Learning Test +   Seo et al. 2016 [32]
Language Fluency   – Tarter et al. 1984 [30]
Confrontation Naming   – Tarter et al. 1984 [30]
Responsive Naming   – Tarter et al. 1984 [30]
Peabody Picture Intelligence Test   – Tarter et al. 1984 [30]
A Verbal Fluency Task +   Takahashi et al. 2017 [28]
The Token Test   – Tarter et al. 1984 [30]
Visuospatial perception MoCA-TR Visuospatial abilities: Clock drawing +   Celikbilek et al. 2018 [22]
MoCA-SR visuoconstructive: Draw a cube and a clock in 11:10 position of clock hands +   Filipovic et al. 2018 [21]
MoCA-TR Visuospatial abilities: Three-dimensional cube-copying task +   Celikbilek et al. 2018 [22]
Hooper Visual Organization Test   – Weinstein et al. 2019 [29]
Block Design   – Tarter et al. 1984 [30]
Tactual Performance +   Tarter et al. 1984 [30]
The Line Tracing Test   – Felipo et al. 2012 [24]
Ideas, abstraction, figural creations and mental flexibility The Animal Fluency Test +   Weinstein et al. 2018 [27]
Trail Making +   Tarter et al. 1984 [30]
MoCA-TR Executive functioning abilities: Trail Making B task +   Celikbilek et al. 2018 [22]
MoCA-TR Executive functioning abilities: Phonemic fluency task +   Celikbilek et al. 2018 [22]
MoCA-TR Executive functioning abilities: Two-item verbal abstraction task +   Celikbilek et al. 2018 [22]
Time to complete trail-making B minus time to complete trail-making A test +   Weinstein et al. 2019 [29]
The Similarities Test +   Weinstein et al. 2019 [29]
  1. aAbbreviations: MOCA-TR Montreal Cognitive Assessment Turkish, MOCA-SR Montreal Cognitive Assessment Serbian, NAFLD Non-alcoholic fatty liver disease, NASH Non-alcoholic steatohepatitis, MMSE Mini mental state examination, T2DM Type 2 diabetes mellitus, CFQ Cognitive failures questionnaire, VFT Verbal fluency task
  2. bPlus (+) = impaired cognitive function observed in NAFLD for specific cognitive test. Negative (−) = no association or similar association observed in NAFLD for specific cognitive test
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BMC Geriatrics

ISSN: 1471-2318

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