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Table 2 Frequency of residents using each of the identified PIM or PIM classes 2007 and 2013

From: Potentially inappropriate medications in relation to length of nursing home stay among older adults

 

2007

2013

Total number of participants in study sample

1881

1305

Long-acting benzodiazepines, n (%)a

112 (6.0)

23 (1.8)

Diazepam (N05BA01), n (%)

15 (0.8)

6 (0.5)

Nitrazepam (N05CD02), n (%)

15 (0.8)

1 (< 0.1)

Flunitrazepam (N05CD03), n (%)

85 (4.5)

18 (1.4)

Anticholinergic drugs, n (%)a

238 (12.7)

105 (8.0)

Gastrointestinal agents, anticholinergic

 Glycopyrronium (A03AB02), n (%)

0

2 (0.2)

Anticholinergic antiemetics

 Scopolamine (A04AD01), n (%)

3 (0.2)

3 (0.2)

Antiarrhythmics class 1A

 Disopyramide (C01BA03), n (%)

2 (0.1)

0

Urinary antispasmodics (excl G04BD12)

 Tolterodine (G04BD07), n (%)

24 (1.3)

4 (0.3)

 Solifenacin (G04BD08), n (%)

1 (< 0.1)

2 (0.2)

 Darifenacin (G04BD10), n (%)

1 (< 0.1)

1 (< 0.1)

 Fesoterodine (G04BD11), n (%)

0

2 (0.2)

Opiates and opioids in combination with antispasmodics

 Ketobemidone and antispasmodics (N02AG02), n (%)

36 (1.9)

23 (1.8)

Anticholinergic anti-Parkinsonian drugs

 Trihexyphenidyl (N04AA01), n (%)

5 (0.3)

4 (0.3)

 Biperiden (N04AA02), n (%)

10 (0.5)

2 (0.2)

Antipsychotic drugs

 Levomepromazine (N05AA02), n (%)

21 (1.1)

13 (1.0)

 Chlorprothixene (N05AF03), n (%)

1 (< 0.1)

0

 Clozapine (N05AH02), n (%)

13 (0.7)

3 (0.2)

Anxiolytics

 Hydroxyzine (N05BB01), n (%)

56 (3.0)

9 (0.7)

Antidepressants, non-selective monoamine reuptake inhibitors

 Clomipramine (N06AA04), n (%)

6 (0.3)

1 (< 0.1)

 Amitriptyline (N06AA09), n (%)

32 (1.7)

19 (1.5)

Antihistamines

 Clemastine (R06AA04), n (%)

14 (0.7)

10 (0.8)

 Alimemazine (R06AD01), n (%)

29 (1.5)

11 (0.8)

 Promethazine (R06AD02), n (%)

4 (0.2)

2 (0.2)

 Meclozine (R06AE05), n (%)

0

1 (< 0.1)

Tramadol (N02AX02), n (%)

119 (6.3)

10 (0.8)

Propiomazine (N05CM06), n (%)

164 (8.7)

25 (1.9)

Codeine, n (%)

13 (0.7)

23 (1.8)

Paracetamol/codeine (N02AJ06), n (%)

13 (0.7)

21 (1.6)

Codeine (R05DA04), n (%)

0

2 (0.2)

Glibenclamide (A10BB01), n (%)

62 (3.3)

7 (0.5)

NSAIDs (COX-inhibitors), n (%)a

97 (5.2)

48 (3.7)

 Indometacin (M01AB01), n (%)

1 (< 0.1)

0

 Diclofenac (M01AB05), n (%)

25 (1.3)

16 (1.2)

 Tenoxicam (M01AC02), n (%)

1 (< 0.1)

0

 Ibuprofen (M01AE01), n (%)

10 (0.5)

8 (0.6)

 Naproxen (M01AE02), n (%)

26 (1.4)

10 (0.8)

 Ketoprofen (M01AE03), n (%)

33 (1.8)

15 (1.1)

 Celecoxib (M01AH01), n (%)

1 (< 0.1)

0

 Etoricoxib (M01AH05), n (%)

1 (< 0.1)

0

 Nabumetone (M01AX01), n (%)

4 (0.2)

0

Antipsychotic drugs, n (%)a

426 (22.6)

209 (16.0)

 Levomepromazine (N05AA02), n (%)

21 (1.1)

13 (1.0)

 Dixyrazine (N05AB01), n (%)

2 (0.1)

0

 Perphenazine (N05AB03), n (%)

6 (0.3)

2 (0.2)

 Haloperidol (N05AD01), n (%)

89 (4.7)

25 (1.9)

 Melperone (N05AD03), n (%)

14 (0.7)

10 (0.8)

 Ziprasidone (N05AE04), n (%)

3 (0.2)

1 (< 0.1)

 Flupenthixol (N05AF01), n (%)

3 (0.2)

3 (0.2)

 Chlorprothixene (N05AF03), n (%)

1 (< 0.1)

0

 Zuclopenthixol (N05AF05), n (%)

21 (1.1)

3 (0.2)

 Clozapine (N05AH02), n (%)

13 (0.7)

3 (0.2)

 Olanzapine (N05AH03), n (%)

92 (4.9)

54 (4.1)

 Quetiapine (N05AH04), n (%)

7 (0.4)

18 (1.4)

 Risperidone (N05AX08), n (%)

178 (9.5)

91 (7.0)

 Aripiprazole (N05AX12), n (%)

0

1 (< 0.1)

PIMs total, n (%)b

903 (48.0)

370 (28.4)

  1. NSAIDs Non-Steroidal Anti-Inflammatory Drugs, COX-inhibitors Cyclooxygenase inhibitors, PIMs Potentially inappropriate medications
  2. aThe frequency and prevalence differ from the sum of PIMs within the class, because some older adults used more than one PIM
  3. bThe frequency and prevalence differ from the sum of PIMs in total, because some older adults used more than one PIM from several PIM classes