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Table 2 The prevalence of the drugs involved in MDIs. Based on prevalence, number of Medicare beneficiaries at risk for an MDI was calculated

From: Prevalence of potentially harmful multidrug interactions on medication lists of elderly ambulatory patients

Medication

% Involved in MDI

CMS Part D beneficiaries

Involved in MDI

amiodarone

27.3

706,029

192,746

methotrexate

23.1

527,799

121,922

bupropion

18.7

1,714,050

320,527

tramadol

16.3

4,266,058

695,367

trazodone

14.6

2,915,625

425,681

cyclobenzaprine

14.3

1,860,548

266,058

fluoxetine

11.5

1,334,205

153,434

ondansetron

10.5

3,153,351

331,102

quetiapine

10.3

1,247,664

128,509

citalopram

9.8

1,684,688

165,099

mirtazapine

8.3

1,345,516

111,678

escitalopram

7.7

2,007,721

154,595

sertraline

7.1

2,683,062

190,497

venlafaxine

6.7

1,075,483

72,057

oxycodone

5.9

4,050,823

238,999

TOTAL

30,572,622

3,568,272

TOTAL psychotropics

16,009,014

1,722,078