From: Patients with Parkinson’s disease predict a lower incidence of colorectal cancer
Categories | N | Pooled RR | 95% CI | P value | Heterogeneity | |
---|---|---|---|---|---|---|
I2 | P′ | |||||
Study design | ||||||
Cohort | 13 | 0.78 | 0.66–0.91 | <0.001 | 90.4% | <0.001 |
Case-control | 4 | 0.78 | 0.65–0.94 | <0.001 | 0% | 0.526 |
Cancer location | ||||||
Colon | 6 | 0.68 | 0.55–0.83 | <0.001 | 86.2% | <0.001 |
Rectum | 5 | 0.89 | 0.83–0.95 | <0.001 | 0 | 0.887 |
Geographical region | ||||||
America | 3 | 0.58 | 0.46–0.74 | <0.001 | 0 | 0.957 |
Europe | 6 | 0.82 | 0.74–0.90 | <0.001 | 51% | 0.070 |
Asia | 4 | 0.83 | 0.51–1.34 | 0.442 | 97% | <0.001 |