Table 1 Baseline characteristics of all included studies in the meta-analysis
From: Patients with Parkinson’s disease predict a lower incidence of colorectal cancer
Author | Year | Country | Study design | N (case) | N (control) | subsite | SQ | adjustment |
|---|---|---|---|---|---|---|---|---|
Guttman [28] | 2003 | Canada | retrospective cohort | 15,304 PD | 30,608 | colon | 6 | age, sex |
OLsen [21] | 2005 | Denmark | retrospective cohort | 14,088 PD | NR | colon +rectum | 6 | age, sex |
Powers [29] | 2005 | USA | Case-control | 352 PD | 484 | colorectal | 6 | age, ethnicity, education, smoking |
Driver [30] | 2007 | USA | prospective cohort | 487 PD | 487 | colorectal | 6 | age |
Fois [22] | 2009 | UK | retrospective cohort | 4355 PD | 574,860 | colon +rectum | 7 | age, sex, year of first hospital admission, region |
Becker [23] | 2010 | UK | retrospective cohort | 2993 PD | 3003 | colorectal | 6 | age, sex, smoking, body mass index, |
Lo [31] | 2010 | USA | retrospective cohort | 692 PD | 761 | colorectal | 7 | age, sex, ethnicity, education (years), annual income, smoking, alcohol consumption, body mass index |
Sun [14] | 2011 | Taiwan, China | retrospective cohort | 4957 PD | 19,828 | colorectal | 6 | age, sex |
Rugbjerg [24] | 2012 | Denmark | retrospective cohort | 20,343 PD | 32,360 | colorectal | 7 | age, sex, calendar year |
Ong [25] | 2014 | UK | retrospective cohort | 219,194 PD | 9,015,614 | colon +rectum | 8 | age, sex, calendar year, region of residence, quintile of patients |
Wirdefeldt [26] | 2014 | Sweden | retrospective cohort | 11,786 PD | 58,930 | colon +rectum | 7 | sex, birth year |
Lin [15] | 2015 | Taiwan, China | retrospective cohort | 62,023 PD | 124,046 | colorectal | 8 | age, sex |
Peretz [34] | 2016 | Israel | retrospective cohort | 7125 PD | NR | colon +rectum | 7 | age, sex, chronological year |
Boursi [27] | 2016 | UK | Case-control | 22,093 cancer | 85,833 | colorectal | 6 | Obesity, diabetes, smoking, alcohol consumption, NSAIDs use, hormone replacement therapy, screening colonoscopy |
Freedman(1) [33] | 2016 | USA | Case-control | 836,947 cancer | 142,869 | colon +rectum | 5 | age, sex, selection year |
Freedman(2) [32] | 2016 | Asia | Case-control | 20,267 cancer | 5558 | colon | 5 | age, sex, selection year |
Park [35] | 2019 | Korea | retrospective cohort | 52,009 PD | 260,045 | colorectal | 8 | age, sex, hypertension, DM, hyperlipidemia |