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Table 4 Correlation of history of fragile fracture, lifestyle and serum biomarkers with osteoporosis or sarcopenia by Logistic Regression

From: Serum concentrations of oxytocin, DHEA and follistatin are associated with osteoporosis or sarcopenia in community-dwelling postmenopausal women

Variables Osteoporosis   Sarcopenia  
OR(95% CI) P value OR(95% CI) P-value
History of fragile fracture (no vs. fracture) 0.30 (0.05–0.71) 0.006 0.45 (0.01–0.86) 0.015
Physical exercise (no vs. high) 0.97 (0.44–3.13) 0.94 1.07 (0.24–2.51) 0.69
Milk consumption (no vs. high) 1.39 (0.57–3.34) 0.46 6.32 (1.04–38.29) 0.045
DHEA (ng/ml) 0.75 (0.61–1.05) 0.06 0.73 (0.51–0.96) 0.032
 T2 0.89 (0.63–1.24) 0.62 0.78 (0.44–2.22) 0.72
 E2 0.67 (0.33–2.65) 0.58 0.90 (0.46–3.12) 0.65
 PTH (pg/ml) 1.01 (0.97–1.04) 0.64 0.97 (0.90–1.04) 0.36
25OHD(ng/ml) 0.98 (0.93–1.07) 0.22 0.51 (0.11–0.82) 0.047
 CTX (pg/ml) 1.02 (0.98–1.05) 0.17 1.02 (0.92–1.12) 0.78
 PINP (ng/ml) 1.12 (0.97–1.48) 0.51 1.07 (0.95–1.17) 0.31
Follistatin (ng/ml) 1.08 (0.56–2.09) 0.17 1.66 (1.19–3.57) 0.022
 Myostatin (ng/ml) 0.95 (0.90–1.13) 0.82 1.01 (0.98–1.03) 0.56
 BDNF (ng/ml) 0.78 (0.38–1.62) 0.50 0.35 (0.07–1.82) 0.35
Oxytocin (pg/ml) 0.75 (0.63–0.98) 0.019 0.88 (0.57–1.01) 0.14
  1. Multivariate logistic analysis was performed after adjusting for age. DHEA Dehydroepiandrosterone, PTH Parathyroid hormone, CTX C-telopeptide collagen crosslinks, P1NP N-terminal propeptide of type 1 collagen, BDNF Brain-derived neurotrophic factor