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Table 1 Baseline characteristics in the total cohort, nonagenarians versus octogenarians

From: Management and outcomes in critically ill nonagenarian versus octogenarian patients

  nonagenarians octogenarians p-value
n = 790 n = 7110  
Male sex n (%) 339 (43%) 3812 (54%) < 0.001
Age
 median (±IQR) 91 (90–93) 83 (81–86) < 0.001
Frailty Score - CFS
 median (±IQR) 5 (4–6) 4 (3–6) < 0.001
 Frailty (CFS > 4) n (%) 454 (58) 2962 (42) < 0.001
ADL
 median (±IQR) 5 (3–6) 6 (4–6) < 0.001
 Disability (ADL ≤4) 151 (44) 805 (26) < 0.001
IQCODE
 median (±IQR) 3.5 (3–4) 3.2 (3–4) < 0.001
 Cognitive Decline (IQCODE ≥3.5) 149 (50) 812 (31) < 0.001
 SOFA score 6 (4–9) 7 (4–10) < 0.001
 median (±IQR)    
ICU length of stay (hours)
 median (±IQR) 84 (24–117) 54 (37–186) < 0.001
 Treatment withdrawn and/or withheld (%) 312 (40) 2302 (33) < 0.001
 NIV n (%) 168 (21) 1794 (23) 0.03
 Intubation n (%) 324 (41) 3685 (52) < 0.001
 Renal replacement therapy n (%) 33 (4) 816 (12) < 0.001
 Vasoactive drugs n (%) 414 (52) 4179 (59) 0.002
Admission diagnosis n (%)    < 0.001
 Respiratory failure 155 (20) 1745 (23)  
 Circulatory failure 136 (17) 968 (14)  
 Combined circulatory & respiratory failure 104 (13) 825 (12)  
 Sepsis 74 (9) 966 (14)  
 Multitrauma w/o Head Injury 23 (3) 128 (2)  
 Trauma with Head Injury 18 (2) 124 (2)  
 Head Injury 29 (4) 166 (2)  
 Intoxication 1 (< 1) 36 (< 1)  
 Cerebral Injury (Non-Traumatic) 38 (5) 469 (7)  
 Emergency Surgery 91 (12) 817 (12)  
 Other 91 (12) 866 (12)  
  1. CFS Clinical Frailty Scale, SOFA Sequential Organ Failure Assessment, ADL Activity of Daily Life measured with the Katz index, IQCODE Informant Questionnaire on COgnitive Decline in the Elderly, ICU Intensive Care Unit, NIV Non-Invasive Ventilation, SD Standard Deviation