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Table 2 Characteristics of participants

From: Applicability of Creatinine-based equations for estimating glomerular filtration rate in elderly Chinese patients

Characteristics Whole Cohort Male Female P
Participants 612 386 226  
Age (Years) 73 (68,80) 75 (69,82) 72 (68,77) 0.000*
BSA(m2) 1.61 (1.48,1.74) 1.69 (1.56,1.81) 1.52 (1.42,1.52) 0.000*
Scr (μmol/l) 119.62 (86.00,190.80) 132.60 (89.60,183.71) 106.50 (74.0,205.8) 0.001*
Bun (mmol/l) 8.18 (6.10,12.18) 8.10(6.17,11.52) 8.26 (6.00,13.13) 0.927*
Alb(g/l) 34.80 (30.70,38.30) 34.60 (30.70,38.00) 35.10 (30.38,39.00) 0.439*
Year group, n(%)
65–79 Year 444 (70.13) 256 (65.20) 188 (79.36) 0.000**
≥80 168 (29.87) 130 (34.80) 38 (20.64)  
mGFR (ml/min/1.73 m2) 42.1 (27.4,62.1) 43.7 (27.9,61.2) 40.1 (25.6,59.2) 0.080*
mGFR, n(%)
  ≥ 90 ml/min/1.73 m2 32 (5.2) 21 (5.4) 11 (4.9)  
 60–89 ml/min/1.73 m2 126 (20.6) 82 (21.2) 44 (19.5)  
 30–59 ml/min/1.73 m2 266 (43.5) 175 (45.3) 91 (40.3)  
 15–29 ml/min/1.73 m2 146 (23.9) 90 (23.3) 56 (24.8)  
  < 15 ml/min/1.73 m2 42 (6.9) 18 (4.7) 24 (10.6)  
eGFR (ml/min/1.73 m2)
 CKD-EPI equation 44.4 (27.1,67.0) 44.8 (29.3,65.8) 43.8 (20.0,69.4) 0.390*
 LMR equation 41.1 (23.9,59.9) 40.9 (25.0,60.0) 41.5 (18.8,63.6) 0.799*
 BIS1 equation 43.6 (30.0,59.5) 43.4 (31.8,57.7) 44.3 (25.0,61.0) 0.778*
 FAS equation 41.8 (27.7,59.3) 42.1 (29.6,58.8) 41.3 (21.8,60.6) 0.391*
 EKFC equation 41.9 (26.4,61.6) 42.2 (28.1,61,1) 40.8 (19.6,64.5) 0.305*
Causes of kidney disease, n(%)
 Primary glomerular disease 101 (16.5) 49 (12.7) 52 (23.0) 0.000**
 Diabetic nephropathy 164 (26.8) 105 (27.2) 59 (26.1) 0.000**
 Hypertensive nephrosclerosis 84 (13.7) 60 (15.5) 24 (10.6) 0.000**
 Obstructive nephropathy 100 (16.3) 49 (12.7) 51 (22.6) 0.000**
 Others 163 (26.6) 123 (31.9) 40 (17.7) 0.000**
Comorbid condition (%)
 Hypertension 460 (75.2) 286 (74.1) 174 (77.0) 0.000**
 Diabetes 293 (47.9) 189 (49.0) 104 (46.2) 0.000**
 Coronary heart disease 225 (36.8) 159 (41.2) 66 (29.2) 0.000**
 Cerebrovascular disease 133 (21.7) 103 (26.7) 30 (13.3) 0.000**
  1. All data were collected from each individual in this study unless otherwise stated. Values for continuous variables are presented as the median and inter-quartile range
  2. Abbreviations: BSA Body surface area, Scr Serum creatinine, Bun Blood urea nitrogen, Alb Albumin, mGFR Measured glomerular filtration rate, eGFR Estimated glomerular filtration rate, CKD-EPI Chronic kidney disease epidemiology collaboration, LMR Lund-Malmö Revised, BIS1 Berlin Initiative Study 1, FAS Full age spectrum equation, EKFC European Kidney Function Consortium. Reference range: Scr, 57-110 μmol/l in male and 53-97 μmol/l in female; Bun, 3.60–9.50 mmol/l; Alb, 44.00–55.00 g/L.
  3. * Non-parametric t-test, **Chi-square test, comparing between male and female