Interaction between cognitive leisure activity and long-chain polyunsaturated fatty acid intake on global cognitive decline in a Japanese longitudinal cohort study: National Institute for Longevity Sciences-Longitudinal Study of Aging

Table 2 Interaction between CLA and LCPUFA intake according to the total number of CLAs

Total number of CLAs with high frequency (more than x)	High frequency		Estimate	SE	Interaction P-value
(x)	(n)	(%)
≥1	517	100.0	-	-	-
≥2	500	96.7	0.32	1.20	0.79
≥3	428	82.8	0.34	0.63	0.59
≥4	302	58.4	−0.23	0.46	0.62
≥5	156	30.2	−1.00	0.51	0.05
6	52	10.1	−1.08	0.94	0.25

Note: Multiple logistic analysis adjusted for sex, age, MMSE score, BMI, education level, marital status, smoking status, alcohol consumption, energy intake, physical activity, employment status, depressive tendency, and history of hypertension, hyperlipidemia, ischemic heart disease, stroke, and diabetes
Fatty acid intake was divided into two groups based on the median according to sex. CLA was divided into two groups based on the frequency of participation: “participation of at least once or more per month” (high) and “once or several times per year or less” (low). CLA, cognitive leisure activity; LCPUFA, long-chain polyunsaturated fatty acid

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